Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3373178 | 0.71 | CNR1 (0.38) | CNR1L3MBTL1NPSR1ACACBTP53 | |
| SCHEMBL4693118 | 0.71 | CA2 (0.42) | CNR1ACACBGRM2SLC6A9PIK3CA | |
| SCHEMBL4692012 | 0.66 | CNR1 (0.41) | CNR1ACACBEPHX2TRPA1 | |
| SCHEMBL4693115 | 0.65 | CA2 (0.39) | CNR1L3MBTL1NPSR1ACACBGRM2 | |
| SCHEMBL3374778 | 0.64 | PPARD (0.40) | CNR1 | |
| SCHEMBL4688487 | 0.64 | CNR1 (0.39) | CNR1EPHX2TRPA1 | |
| SCHEMBL4693113 | 0.64 | CA2 (0.40) | CNR1NPSR1ACACBATMSMN1; SMN2 | |
| SCHEMBL24637811 | 0.62 | CA2 (0.46) | L3MBTL1NPSR1ACACBSLC6A9ATM | |
| SCHEMBL28788509 | 0.59 | KDM4E (0.45) | L3MBTL1NPSR1TP53POLBSMN1; SMN2 | |
| SCHEMBL23361197 | 0.59 | PKM (0.50) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496838-B1 | SUBSTITUTED AMIDES | MERCK SHARP & DOHME (US) | 2010-11-03 | — | — | EP | disclosed |