SCHEMBL3374229

SCHEMBL3374229

C=CC(Cc1ccc(-c2ccccc2-c2nnnn2C(c2ccccc2)(c2ccccc2)c2ccccc2)cc1)OC(=O)c1[nH]c(CCC)nc1C(C)(C)O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 7/20 0.44
AGTR2 P50052 7/20 0.44
AGT P01019 2/20 0.39
ABCC3 O15438 1/20 0.34
ABCC4 O15439 1/20 0.34
ABCB11 O95342 1/20 0.34
CYP3A4 P08684 1/20 0.34
PDE4D Q08499 1/20 0.34
PDE3A Q14432 1/20 0.34
SLCO1B3 Q9NPD5 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7301888 0.86 AGTR1 (0.48) AGTR1AGTR2AGTABCC3ABCC4
SCHEMBL7308714 0.81 AGT (0.47) AGTR1AGTR2AGTABCC3ABCC4
SCHEMBL7303806 0.80 AGTR1 (0.44) AGTR1AGTR2AGTABCC3ABCC4
SCHEMBL8845361 0.79 AGTR1 (0.43) AGTR1AGTR2AGTABCC3ABCC4
SCHEMBL8845233 0.76 AGTR1 (0.47) AGTR1AGTR2AGT
SCHEMBL7303313 0.75 AGT (0.46) AGTR1AGTR2AGT
SCHEMBL7304989 0.75 AGTR1 (0.48) AGTR1AGTR2AGT
SCHEMBL9203557 0.75 AGTR1 (0.48) AGTR1AGTR2AGT
SCHEMBL7312371 0.75 AGTR1 (0.46) AGTR1AGTR2AGT
SCHEMBL8861130 0.73 AGTR1 (0.55) AGTR1AGTR2AGTABCC3ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076492-B2 Process for preparing trityl olmesartan medoxomil and olmesartan medoxomil CIPLA LIMITED (IN) 2011-12-13 US disclosed
US-20100160643-A1 Process for Preparing Trityl Olmesartan Medoxomil and Olmesartan Medoxomil CIPLA LIMITED (IN) 2010-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160643-A1 Process for Preparing Trityl Olmesartan Medoxomil and Olmesartan Medoxomil MED1, AGTR1, MED12 AGTR1 2/4885AGTR2 4/4885AGT 39/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.