Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL6336331 | 1.00 | ALDH1A1 (0.72) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL1894404 | 1.00 | ALDH1A1 (0.72) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL384127 | 1.00 | — | — | |
| Imidazole SCHEMBL28097519 | 0.97 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL15152163 | 0.97 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL28097518 | 0.97 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Oxalic Acid SCHEMBL7766522 | 0.92 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Oxalic Acid SCHEMBL1077269 | 0.92 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL5838661 | 0.91 | ALDH1A1 (0.87) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL5838654 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967484-B1 | METHODS FOR DETECTING OR ASSAYING VIRUS | ADVANCED LIFE SCIENCE INST INC (JP) | 2007-05-02 | — | — | EP | claimed |
| EP-0777656-B1 | NOVEL DNA-TARGETED ALKYLATING AGENTS | AUCKLAND DIVISION CANCER SOC O (NZ) | 2004-04-14 | — | — | EP | claimed |
| EP-2230288-B1 | METAL-ORGANIC FRAMEWORKS IN REFRIGERATION/HEATING MACHINES | BASF SE (DE) | 2016-05-25 | — | — | EP | disclosed |
| EP-2230288-A2 | Metal-organic frameworks in refrigeration/heating machines | BASF SE (DE) | 2010-09-22 | — | — | EP | disclosed |