Imidazole

Imidazole

SCHEMBL1894404

O=C(O)O.c1c[nH]cn1.c1c[nH]cn1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.72
FKBP5 Q13451 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidazole SCHEMBL6336331 1.00 ALDH1A1 (0.72) ALDH1A1FKBP5
Imidazole SCHEMBL384127 1.00
Imidazole SCHEMBL3374317 1.00 ALDH1A1 (0.72) ALDH1A1FKBP5
Imidazole SCHEMBL28097519 0.97 ALDH1A1 (0.68) ALDH1A1FKBP5
Imidazole SCHEMBL15152163 0.97 ALDH1A1 (0.68) ALDH1A1FKBP5
Imidazole SCHEMBL28097518 0.97 ALDH1A1 (0.68) ALDH1A1FKBP5
Oxalic Acid SCHEMBL7766522 0.92 ALDH1A1 (0.68) ALDH1A1FKBP5
Oxalic Acid SCHEMBL1077269 0.92 ALDH1A1 (0.68) ALDH1A1FKBP5
Imidazole SCHEMBL5838661 0.91 ALDH1A1 (0.87) ALDH1A1FKBP5
Imidazole SCHEMBL5838654 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110249052-B Synthetic guide molecules, compositions, and methods related thereto 爱迪塔斯医药公司 2024-04-12 CN claimed
US-11603321-B2 Rechargeable aluminum ion battery EVERON24, INC. (US) 2023-03-14 US claimed
CN-114524812-A Crystal form preparation and synthesis method of 1, 4-dihydro-1, 6-naphthyridine compound 湖南凯铂生物药业有限公司 2022-05-24 CN claimed
EP-3565895-A1 SYNTHETIC GUIDE MOLECULES, COMPOSITIONS AND METHODS RELATING THERETO Editas Medicine, Inc. (US) 2019-11-13 EP claimed
EP-3526878-A1 RECHARGEABLE ALUMINUM ION BATTERY Everon24 LLC (US) 2019-08-21 EP claimed
US-20180353401-A1 A HAIR CARE COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-12-13 US claimed
US-20180344606-A1 A HAIR CARE COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-12-06 US claimed
EP-3383498-A1 A HAIR CARE COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP Investments LLC (US) 2018-10-10 EP claimed
WO-2018126176-A1 SYNTHETIC GUIDE MOLECULES, COMPOSITIONS AND METHODS RELATING THERETO EDITAS MEDICINE, INC. (US) 2018-07-05 WO claimed
US-20180138554-A1 Rechargeable Aluminum Ion Battery Alsym Energy, Inc. 2018-05-17 US claimed
WO-2018017390-A1 A HAIR CARE COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-01-25 WO claimed
WO-2018017408-A1 A HAIR CARE COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-01-25 WO claimed
WO-2017096005-A1 A HAIR CARE COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2017-06-08 WO claimed
WO-2017096015-A1 A HAIR CARE COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2017-06-08 WO claimed
CN-104945358-A Method for synthesizing allylsuccinic anhydride SHANGHAI DONGYUE BIOCHEM CO LTD 2015-09-30 CN claimed
CN-1020733-C PROCESS FOR PREPARING COVALENT CONJUNCT AGENT OF BACTERIAL POLYSACCHARIDE AND IMMUNOGEN PROTEIN MC CO LTD (US) 1993-05-19 CN claimed
CN-85104164-A Preparation method of covalent conjugate of bacterial polysaccharide and immunogen protein 1987-02-04 CN claimed
JP-56115775-A None JP disclosed
CN-1069264-A Butyramide CIBA GEIGY AG (CH) 1993-02-24 CN disclosed
JP-S56115775-A PREPARATION OF DIHYDROXYMETHYLPYRIDINE DICARBAMATE SHINSEN IYAKU KK 1981-09-11 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180344606-A1 A HAIR CARE COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF DPM1, SUCLG1, POLR1C ALDH1A1 1175/4885FKBP5 2849/4885
US-20180353401-A1 A HAIR CARE COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF DPM1, POLR1C, SUCLG1 ALDH1A1 482/4885FKBP5 3021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.