Imidazole

Imidazole

SCHEMBL384127

O=C(O)O.c1c[nH]cn1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidazole SCHEMBL6336331 1.00 ALDH1A1 (0.72)
Imidazole SCHEMBL1894404 1.00 ALDH1A1 (0.72)
Imidazole SCHEMBL3374317 1.00 ALDH1A1 (0.72)
Imidazole SCHEMBL28097519 0.97 ALDH1A1 (0.68)
Imidazole SCHEMBL15152163 0.97 ALDH1A1 (0.68)
Imidazole SCHEMBL28097518 0.97 ALDH1A1 (0.68)
Oxalic Acid SCHEMBL7766522 0.92 ALDH1A1 (0.68)
Oxalic Acid SCHEMBL1077269 0.92 ALDH1A1 (0.68)
Imidazole SCHEMBL5838661 0.91 ALDH1A1 (0.87)
Imidazole SCHEMBL5838654 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3687652-B1 HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER FOR RETENTION OF ACIDIC ANALYTES WATERS TECHNOLOGIES CORP (US) 2025-07-09 EP claimed
CN-120025765-A Electrolytic adhesive, preparation method thereof and electrolytic adhesive tape 新纶光电材料(常州)有限公司 2025-05-23 CN claimed
CN-119823677-A Electrolytic adhesive and adhesive tape and preparation method thereof 新纶电子材料(常州)有限公司 2025-04-15 CN claimed
US-12252557-B2 Charged surface reversed phase chromatographic materials method for analysis of glycans modified with amphipathic, strongly basic moieties WATERS TECHNOLOGIES CORPORATION (US) 2025-03-18 US claimed
US-20240209009-A1 PEPTIDES COMPRISING A PHOSPHORYLCHOLINE CONJUGATE AND METHODS OF SYNTHESIZING SAME TARSIER PHARMA LTD. (IL) 2024-06-27 US claimed
CN-115322355-B Boc functionalized carbonate monomer, boc functionalized polycarbonate and preparation method thereof 大连理工大学 2024-03-19 CN claimed
EP-4326738-A1 PEPTIDES COMPRISING A PHOSPHORYLCHOLINE CONJUGATE AND METHODS OF SYNTHESIZING SAME Tarsier Pharma Ltd. (IL) 2024-02-28 EP claimed
CN-117500817-A Peptides comprising phosphorylcholine conjugates and methods of synthesizing the same 塔西亚制药公司 2024-02-02 CN claimed
CN-117054585-A Charged surface reversed phase chromatography material method for analysis of glycans modified with amphiphilic strong basic moieties 沃特世科技公司 2023-11-14 CN claimed
CN-109154604-B Charged surface reversed phase chromatography material method for analysis of glycans modified with amphiphilic strong basic moieties 沃特世科技公司 2023-07-21 CN claimed
EP-1859800-B1 Medicament comprising alkyl esters of imidazole carboxylic acid for the treatment of neurodegenerative disorders MEDDEV INC (US) 2009-12-30 EP claimed
EP-1828099-A1 SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS Cardimone Pharma Corporation (CA) 2007-09-05 EP claimed
WO-2006088525-A1 SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS CARDIOME PHARMA CORP. (CA) 2006-08-24 WO claimed
US-20060094880-A9 Synthetic process for trans-aminocyclohexyl ether compounds BARRETT ANTHONY G M 2006-05-04 US claimed
WO-2005016242-A2 SYNTHETIC PROCESS FOR TRANS-AMINOCYCLOHEXYL ETHER COMPOUNDS CARDIOME PHARMA CORP. (CA) 2005-02-24 WO claimed
US-20050038256-A1 Synthetic process for trans-aminocyclohexyl ether compounds CARDIOME PHARMA CORP. (CA) 2005-02-17 US claimed
US-20030180804-A1 Solid phase synthesis of chemical libraries CORVAS INTERNATIONAL, INC 2003-09-25 US claimed
WO-2003037326-A1 SOLID PHASE SYNTHESIS OF CHEMICAL LIBRARIES CORVAS INTERNATIONAL, INC. (US) 2003-05-08 WO claimed
EP-0904323-B1 INHIBITION OF BACTERIAL GROWTH BIOCOTE LTD (GB) 2001-07-18 EP claimed
EP-0896600-B1 NON-THROMBOGENIC AND ANTI-THROMBOGENIC POLYMERS LUTHRA AJAY KUMAR (GB) 2000-01-12 EP claimed