Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Imidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL1894404 | 1.00 | ALDH1A1 (0.72) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL384127 | 1.00 | — | — | |
| Imidazole SCHEMBL3374317 | 1.00 | ALDH1A1 (0.72) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL28097519 | 0.97 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL15152163 | 0.97 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL28097518 | 0.97 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Oxalic Acid SCHEMBL7766522 | 0.92 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Oxalic Acid SCHEMBL1077269 | 0.92 | ALDH1A1 (0.68) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL5838661 | 0.91 | ALDH1A1 (0.87) | ALDH1A1FKBP5 | |
| Imidazole SCHEMBL5838654 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852888-B2 | Carboxylic acid derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2005-02-08 | — | — | US | disclosed |
| EP-1084100-B1 | DIFLUOROALKENCARBOXANILIDES AND PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2004-07-14 | — | — | EP | disclosed |
| EP-0661289-B1 | Vinyl carboxamide derivatives as insecticides and acaricides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-03-03 | — | — | EP | disclosed |
| US-20030216467-A1 | Carboxylic acid derivatives | SYNGENTA CROP PROTECTION, INC. (FORMERLY KNOWN AS NOVARTIS CROP PROTECTION, INC.) | 2003-11-20 | — | — | US | disclosed |
| EP-1084100-A1 | DIFLUOROALKENCARBOXANILIDES AND PESTICIDAL COMPOSITIONS | Novartis AG (CH) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062866-A1 | DIFLUOROALKENCARBOXANILIDES AND PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 1999-12-09 | — | — | WO | disclosed |
| US-5763481-A | PESTICIDES; INSECTICIDES, MITICIDES | NOVARTIS CORPROATION (US) | 1998-06-09 | — | — | US | disclosed |
| US-5545630-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1996-08-13 | — | — | US | disclosed |
| US-5439908-A | Insecticides | CIBA-GEIGY CORPORATION (US) | 1995-08-08 | — | — | US | disclosed |
| EP-0661289-A1 | Vinyl carboxamide derivatives as insecticides and acaricides | CIBA-GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| US-5358957-A | Agrochemicals; pesticides | CIBA-GEIGY CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216467-A1 | Carboxylic acid derivatives | CLIC1, CNPY3, HCFC1 | ALDH1A1 1211/4885FKBP5 3895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.