Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476574 | 0.80 | MAPT (0.42) | MAPTKDM4EGAAMEN1ALDH1A1 | |
| SCHEMBL1335991 | 0.73 | MAPT (0.56) | MAPTKDM4EGAAMEN1ALDH1A1 | |
| SCHEMBL8930736 | 0.73 | KDM4E (0.45) | KDM4EGAAMEN1ALDH1A1KMT2A | |
| SCHEMBL9788857 | 0.72 | MAPT (0.48) | MAPTKDM4EGAAMEN1ALDH1A1 | |
| SCHEMBL6761348 | 0.71 | ALDH1A1 (0.48) | MAPTGAAMEN1ALDH1A1KMT2A | |
| SCHEMBL8893645 | 0.70 | MAPT (0.49) | MAPTGAAMEN1ALDH1A1KMT2A | |
| SCHEMBL9158033 | 0.70 | ALDH1A1 (0.46) | MAPTKDM4EGAAMEN1ALDH1A1 | |
| SCHEMBL3375185 | 0.69 | RRM2 (0.38) | MAPTKDM4EGAAMEN1ALDH1A1 | |
| SCHEMBL2677107 | 0.69 | MAPT (0.71) | MAPTKDM4EGAAMEN1ALDH1A1 | |
| SCHEMBL29386651 | 0.69 | MAPT (0.46) | MAPTKDM4EGAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943809-B2 | Solvent resistant thin film composite membrane and its preparation | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-04-17 | — | — | US | claimed |
| US-20170065937-A1 | SOLVENT RESISTANT THIN FILM COMPOSITE MEMBRANE AND ITS PREPARATION | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2017-03-09 | — | — | US | claimed |
| US-12036515-B2 | Thin-film composite membrane and methods of making and using the same | THE PENN STATE RESEARCH FOUNDATION (PA) | 2024-07-16 | — | — | US | disclosed |
| US-20210370240-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | THE PENN STATE RESEARCH FOUNDATION | 2021-12-02 | — | — | US | disclosed |
| EP-3860743-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | The Penn State Research Foundation (US) | 2021-08-11 | — | — | EP | disclosed |
| WO-2020072594-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | THE PENN STATE RESEARCH FOUNDATION (US) | 2020-04-09 | — | — | WO | disclosed |
| US-9943809-B2 | Solvent resistant thin film composite membrane and its preparation | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-04-17 | — | — | US | disclosed |
| US-20170065937-A1 | SOLVENT RESISTANT THIN FILM COMPOSITE MEMBRANE AND ITS PREPARATION | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2017-03-09 | — | — | US | disclosed |
| US-7727434-B2 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070039874-A1 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY | 2007-02-22 | — | — | US | disclosed |
| US-5693227-A | POLYMERIZATION OF MOLECULES HAVING ELECTROPHILIC AND NUCLEOPHILIC SUBSTITUENTS ON THE SAME OR DIFFERENT MOLECULES; REGENERATION OF AMINOPYRIDINE CATALYSTS | IONICS, INCORPORATED (US) | 1997-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12036515-B2 | Thin-film composite membrane and methods of making and using the same | PORCN, MLEC, FLOT1 | MAPT 3412/4885KDM4E 3071/4885GAA 4229/4885 |
| US-20210370240-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | PORCN, MLEC, FLOT1 | MAPT 3412/4885KDM4E 3071/4885GAA 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.