SCHEMBL3375286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3374401	0.91	TSHR (0.52)	TSHRALDH1A1AOC3CARM1PRMT6
	SCHEMBL25397829	0.90	TSHR (0.50)	TSHRALDH1A1AOC3CARM1PRMT6
	SCHEMBL3376961	0.76	TSHR (0.50)	TSHRALDH1A1AOC3CARM1PRMT6
	SCHEMBL642317	0.76	CRHBP (0.61)	TSHRALDH1A1AOC3CARM1PRMT6
	SCHEMBL11881187	0.76	NR1H2 (0.62)	TSHRALDH1A1AOC3CARM1PRMT6
	Hydrochloric Acid SCHEMBL27388371	0.74	CRHBP (0.59)	TSHRALDH1A1AOC3CARM1PRMT6
	SCHEMBL3371521	0.74	TSHR (0.64)	TSHRALDH1A1AOC3LMNAADRA2B
	Nitrogen SCHEMBL4600396	0.73	CRHBP (0.58)	TSHRALDH1A1AOC3CARM1PRMT6
	SCHEMBL5014268	0.72	TSHR (1.00)	TSHRALDH1A1AOC3CARM1PRMT6
	Dibemethine SCHEMBL276863	0.72	ALDH1A1 (0.70)	TSHRALDH1A1AOC3CARM1PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.