Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 4/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.40 |
| ▸ | HTR3B | O95264 | 3/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNG | P07510 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2087087 | 0.81 | DYRK1A (0.48) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL3695594 | 0.77 | DYRK1A (0.46) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL6411553 | 0.76 | DYRK1A (0.46) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL2086084 | 0.71 | NPC1 (0.67) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL2087519 | 0.69 | ALDH1A1 (0.52) | HTR3ASMN1; SMN2CHRNA7MAPTLMNA | |
| SCHEMBL2262277 | 0.69 | RAB9A (0.50) | HTR3ASMN1; SMN2CHRNA7KDM4EHSD17B10 | |
| SCHEMBL12441936 | 0.68 | NPC1 (0.68) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL2086948 | 0.68 | NPC1 (0.68) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL2087490 | 0.68 | NPC1 (0.68) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7424386 | 0.68 | DYRK1A (0.49) | HTR3ASMN1; SMN2CHRNA7KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742944-B1 | INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARM CORP (US) | 2010-11-10 | — | — | EP | claimed |