Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH4 | P08319 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10416391 | 1.00 | ADH1C (0.43) | ADH1CADH1AADH4DRD3DRD2 | |
| SCHEMBL3374356 | 0.95 | DRD3 (0.44) | ADH1CADH1AADH4DRD3DRD2 | |
| SCHEMBL517191 | 0.90 | ADH1A (0.43) | ADH1CADH1AADH4DRD3DRD2 | |
| SCHEMBL3373689 | 0.90 | ADH1C (0.41) | ADH1CADH1AADH4DRD3DRD2 | |
| SCHEMBL6967318 | 0.89 | ADH1C (0.37) | ADH1CADH1AADH4DRD3DRD2 | |
| SCHEMBL6961343 | 0.89 | ADH1C (0.37) | ADH1CADH1AADH4DRD3DRD2 | |
| SCHEMBL8397203 | 0.89 | GBA1 (0.39) | ADH1CADH1AADH4DRD3DRD2 | |
| SCHEMBL6680792 | 0.89 | GNAI3 (0.37) | ADH1CADH1AADH4DRD3DRD2 | |
| SCHEMBL627799 | 0.87 | ADH1A (0.45) | ADH1CADH1AADH4DRD3DRD2 | |
| SCHEMBL12663274 | 0.87 | DRD3 (0.43) | ADH1CADH1ADRD3DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324091-A1 | Pyrazolone Derivative | KOWA COMPANY, LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| EP-2172458-A1 | PYRAZOLONE DERIVATIVE | Kowa Company, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324091-A1 | Pyrazolone Derivative | SERPINE1, SERPINC1, TFPI | ADH1C 511/4885ADH1A 412/4885ADH4 1260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.