Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALPI | P09923 | 2/20 | 0.44 |
| ▸ | ALPG | P10696 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.38 |
| ▸ | GLRB | P48167 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380902 | 0.85 | ALPL (0.43) | ALPLPOLBALPIALPGMAPT | |
| SCHEMBL3376046 | 0.84 | HRH3 (0.44) | POLBMAPTKMT2AMEN1TSHR | |
| SCHEMBL3377343 | 0.83 | SOS1 (0.44) | POLBHRH3 | |
| SCHEMBL3378015 | 0.83 | HRH3 (0.45) | POLBHRH3TP53 | |
| SCHEMBL3380289 | 0.83 | HRH3 (0.41) | MAPTKMT2AMEN1TSHRLMNA | |
| SCHEMBL3380356 | 0.82 | HRH3 (0.42) | TSHRLMNAHRH3 | |
| SCHEMBL3376233 | 0.81 | HRH3 (0.42) | POLBLMNAHRH3 | |
| SCHEMBL3377859 | 0.81 | HRH3 (0.44) | POLBHRH3 | |
| SCHEMBL3378936 | 0.81 | HRH3 (0.48) | POLBKMT2AHRH3 | |
| SCHEMBL3377762 | 0.80 | HRH3 (0.41) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899296-B1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | claimed |