Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | ALPI | P09923 | 3/20 | 0.43 |
| ▸ | ALPG | P10696 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.41 |
| ▸ | GLRB | P48167 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3376760 | 0.85 | ALPL (0.44) | ALPLPOLBALPIALPGMAPT | |
| SCHEMBL3377402 | 0.84 | HTR2A (0.39) | POLBKMT2AMEN1 | |
| SCHEMBL3379302 | 0.84 | CXCR4 (0.42) | POLB | |
| SCHEMBL3377408 | 0.83 | SIGMAR1 (0.42) | TSHRKMT2AMEN1LMNA | |
| SCHEMBL3412556 | 0.83 | BCHE (0.42) | POLBRAB9ALMNA | |
| SCHEMBL3377710 | 0.83 | SOS1 (0.38) | POLBKMT2AMEN1 | |
| SCHEMBL3376778 | 0.83 | HTR2A (0.37) | POLBLMNA | |
| SCHEMBL3379997 | 0.83 | CXCR4 (0.41) | POLBKMT2AMEN1TDP1 | |
| SCHEMBL3376674 | 0.83 | CXCR4 (0.41) | POLBKMT2ALMNA | |
| SCHEMBL3377315 | 0.83 | ALDH1A1 (0.41) | GLRA3GLRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899296-B1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | claimed |