Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226373 | 0.83 | CA2 (0.45) | TAAR1HTR2AHRH1CYP2C19CA1 | |
| Hydrochloric Acid SCHEMBL320519 | 0.82 | HRH1 (0.52) | TAAR1HTR2AGABBR2GABBR1HRH1 | |
| SCHEMBL4554083 | 0.81 | TAAR1 (0.48) | TAAR1HTR2AGABBR2GABBR1CHRNB2 | |
| SCHEMBL30600579 | 0.81 | CYP2C19 (0.41) | TAAR1HTR2AGABBR2GABBR1CYP2D6 | |
| SCHEMBL988364 | 0.81 | LMNA (0.43) | TAAR1HTR2ACYP2C19CA1CA2 | |
| SCHEMBL9184436 | 0.81 | TAAR1 (0.48) | TAAR1HTR2AGABBR2GABBR1CHRNB2 | |
| SCHEMBL1663424 | 0.81 | SRC (0.53) | TAAR1HTR2AGABBR2GABBR1CHRNB2 | |
| Hydrochloric Acid SCHEMBL31111546 | 0.79 | LMNA (0.42) | TAAR1HTR2ACA1CA2CA9 | |
| SCHEMBL3808204 | 0.79 | EPHX1 (0.47) | TAAR1SLC6A4SLC6A3CYP1A2CA1 | |
| SCHEMBL3472313 | 0.78 | AOC3 (0.43) | TAAR1HRH1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996544-B1 | A METHOD OF PREPARATION OF (R)-(-)-5(2-AMINOPROPYL)-2-METHOXYBENZENESULFONAMIDE | ZENTIVA KS (CZ) | 2010-11-10 | — | — | EP | disclosed |
| US-7638649-B2 | Method of preparation of (R)-(−)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide | ZENTIVA, K.S. (CZ) | 2009-12-29 | — | — | US | disclosed |
| US-20080319225-A1 | Method of Preparation of (R)-(-)-5(2-Aminopropyl)-2-Methoxybenzenesulfonamide | ZENTIVA, A.S. (CZ) | 2008-12-25 | — | — | US | disclosed |
| EP-1996544-A1 | A METHOD OF PREPARATION OF (R)-(-)-5(2-AMINOPROPYL)-2-METHOXYBENZENESULFONAMIDE | Zentiva, a.s. (CZ) | 2008-12-03 | — | — | EP | disclosed |
| WO-2005075415-A1 | A METHOD OF PREPARATION OF (R)-(-)-5(2-AMINOPROPYL)-2-METHOXYBENZENESULFONAMIDE | ZENTIVA, A.S. (CZ) | 2005-08-18 | — | — | WO | disclosed |
| WO-2003035608-A1 | A METHOD OF THE PREPARATION OF (R)-(-)-5`2-`2-(2-ETHOXYPHENOXY) ETHYLAMINO! PROPYL!-2-METHOXYBENZENESULPHONAMIDE (TAMSULOSIN) | LECIVA, A.S. (CZ) | 2003-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319225-A1 | Method of Preparation of (R)-(-)-5(2-Aminopropyl)-2-Methoxybenzenesulfonamide | NPSR1, TPSAB1, TPSB2 | TAAR1 98/4885HTR2A 354/4885GABBR2 1362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.