SCHEMBL3377478

SCHEMBL3377478

Cc1c2c3ccccc3nc-2n(C)c2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 1/20 0.47
FGFR1 P11362 1/20 0.47
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
CYP11B2 P19099 1/20 0.45
GPR3 P46089 1/20 0.45
KDM4E B2RXH2 8/20 0.45
ALDH1A1 P00352 8/20 0.45
TP53 P04637 6/20 0.45
MAPT P10636 5/20 0.45
NPC1 O15118 5/20 0.45
RAB9A P51151 5/20 0.45
HSD17B10 Q99714 5/20 0.45
PKM P14618 4/20 0.45
GAA P10253 2/20 0.45
ALOX15 P16050 2/20 0.45
TERT O14746 1/20 0.45
CASP3 P42574 1/20 0.45
MAPK1 P28482 2/20 0.45
TLR9 Q9NR96 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21220860 0.82 ALDH1A1 (0.44) PDGFRBFGFR1MEN1KMT2AGPR3
SCHEMBL21660624 0.80 MAPK1 (0.51) MEN1KMT2AKDM4EALDH1A1TP53
SCHEMBL15315659 0.78 MEN1 (0.61) PDGFRBFGFR1MEN1KMT2AKDM4E
SCHEMBL3291144 0.76 TERT (0.53) MEN1KMT2ACYP11B2GPR3KDM4E
SCHEMBL17127692 0.76 F2 (0.40) PDGFRBFGFR1MEN1KMT2AKDM4E
Anisole SCHEMBL30630097 0.73 RAB9A (0.43) MEN1KMT2AKDM4EALDH1A1TP53
SCHEMBL21220776 0.73 KMT2A (0.51) PDGFRBFGFR1MEN1KMT2AKDM4E
SCHEMBL21660663 0.73 ESR1 (0.42) MEN1KMT2AKDM4EALDH1A1TP53
SCHEMBL20405089 0.73 ALDH1A1 (0.61) PDGFRBFGFR1MEN1KMT2AKDM4E
SCHEMBL1171430 0.73 MEN1 (0.69) MEN1KMT2AKDM4EALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1631677-B1 SYSTEM FOR DETECTING POLYNUCLEOTIDES INVESTIGEN INC (US) 2010-11-17 EP disclosed
CN-1894423-A System for detecting polynucleotides INVESTIGEN INC (US) 2007-01-10 CN disclosed