Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | FLT3 | P36888 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30629240 | 1.00 | RAB9A (0.63) | RAB9ANPC1KMT2AMEN1TSHR | |
| SCHEMBL31060243 | 0.88 | FLT3 (0.71) | FLT3MAPTKDM4EBCAT1PDGFRB | |
| SCHEMBL1378971 | 0.87 | ALDH1A1 (0.63) | RAB9ANPC1KMT2AMEN1FLT3 | |
| SCHEMBL11112195 | 0.86 | FLT3 (0.58) | RAB9ANPC1KMT2AMEN1FLT3 | |
| SCHEMBL8761540 | 0.84 | MAPT (0.72) | RAB9ANPC1KMT2AMEN1TSHR | |
| SCHEMBL29527237 | 0.83 | KDM4E (0.66) | FLT3KDM4EBCAT1ALDH1A1TAS1R3 | |
| SCHEMBL335319 | 0.83 | KDM4E (0.66) | FLT3KDM4EBCAT1ALDH1A1TAS1R3 | |
| SCHEMBL2033212 | 0.82 | KDM4E (0.81) | RAB9ANPC1MAPK1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL11498190 | 0.82 | KDM4E (0.64) | FLT3KDM4EBCAT1ALDH1A1TAS1R3 | |
| SCHEMBL5508127 | 0.82 | MAPT (0.57) | TSHRFLT3SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013114040-A1 | NOVEL COMPOUNDS AND COMPOSITIONS USED AS ANTICANCER AGENTS | UNIVERSITE PARIS DIDEROT - PARIS 7 (FR) | 2013-08-08 | — | — | WO | disclosed |
| WO-2013114040-A1 | NOVEL COMPOUNDS AND COMPOSITIONS USED AS ANTICANCER AGENTS | UNIVERSITE PARIS DIDEROT - PARIS 7 (FR) | 2013-08-08 | — | — | WO | disclosed |
| EP-1653944-B1 | HETEROCYCLIC COMPOUNDS USEFUL AS MALONYL-COA DECARBOXYLASE INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-7696365-B2 | Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-04-13 | — | — | US | disclosed |
| EP-1653944-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS MALONYL-COA DECARBOXYLASE INHIBITORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005011670-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS MALONYL-COA DECARBOXYLASE INHIBITORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-02-10 | — | — | WO | disclosed |
| US-20050026969-A1 | Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026969-A1 | Heterocyclic compounds useful as malonyl-CoA decarboxylase inhibitors | ACACA, ACACB, PC | RAB9A 3202/4885NPC1 643/4885KMT2A 1162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.