Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375950 | 0.84 | CXCR4 (0.44) | MEN1KMT2ATP53CHRNB2CHRNA4 | |
| SCHEMBL4646535 | 0.84 | MEN1 (0.52) | MEN1KMT2APOLBALDH1A1HRH3 | |
| SCHEMBL3377218 | 0.83 | POLB (0.50) | MEN1KMT2APOLBALDH1A1HRH3 | |
| SCHEMBL3376594 | 0.80 | HRH3 (0.50) | MEN1KMT2APOLBHRH3KCNH2 | |
| SCHEMBL3376165 | 0.80 | CACNA1I (0.52) | KMT2AALDH1A1HTTKCNH2MCHR1 | |
| SCHEMBL3380191 | 0.79 | HRH3 (0.49) | MEN1KMT2APOLBHRH3KCNH2 | |
| SCHEMBL3376038 | 0.79 | ALDH1A1 (0.52) | POLBALDH1A1HRH3KCNH2MCHR1 | |
| SCHEMBL3381187 | 0.78 | HRH3 (0.47) | MEN1KMT2APOLBALDH1A1HRH3 | |
| SCHEMBL4649673 | 0.76 | HRH3 (0.43) | MEN1KMT2AALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL19122104 | 0.74 | HTR1A (0.49) | KMT2AALDH1A1HTTROCK1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899296-B1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | claimed |