Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783801 | 0.85 | CYP2D6 (0.51) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL30189619 | 0.85 | CYP2D6 (0.51) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL706675 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL5058376 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL774393 | 0.82 | ALDH1A1 (0.53) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL1911809 | 0.82 | ALDH1A1 (0.53) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL2061056 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4EIDO1ADRA1ATAAR1 | |
| SCHEMBL5009715 | 0.81 | MEN1 (0.56) | ALDH1A1CYP3A4MEN1MAPTKMT2A | |
| SCHEMBL11715214 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL774392 | 0.80 | ALDH1A1 (0.57) | ALDH1A1CYP3A4MEN1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119098205-A | Nitrogen-doped porous carbon-loaded cobalt monoatomic catalyst and preparation method and application thereof | 南京理工大学 | 2024-12-10 | — | — | CN | claimed |
| EP-3796905-B1 | ESTROGEN RECEPTOR BETA LIGANDS FOR THE PREVENTION AND TREATMENT OF MULTIPLE SCLEROSIS (MS) AND OTHER DEMYELINATING, INFLAMMATORY AND NEURODEGENERATIVE DISEASES | UNIV ILLINOIS (US) | 2025-08-06 | — | — | EP | disclosed |
| US-20250223264-A1 | ESTROGEN RECEPTOR BETA LIGANDS FOR THE PREVENTION AND TREATMENT OF MULTIPLE SCLEROSIS (MS) AND OTHER DEMYELINATING, INFLAMMATORY AND NEURODEGENERATIVE DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-07-10 | — | — | US | disclosed |
| US-12286407-B2 | Estrogen receptor beta ligands for the prevention and treatment of multiple sclerosis (MS) and other demyelinating, inflammatory and neurodegenerative diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2025-04-29 | — | — | US | disclosed |
| CN-119098205-A | Nitrogen-doped porous carbon-loaded cobalt monoatomic catalyst and preparation method and application thereof | 南京理工大学 | 2024-12-10 | — | — | CN | disclosed |
| US-20240124488-A1 | AZA-CRYPTOPHANES, PROCESSES FOR PREPARATION THEREOF, AND THEIR USES | UNIVERSITE DE CAEN NORMANDIE (FR) | 2024-04-18 | — | — | US | disclosed |
| CN-117843515-A | Aromatic amino acid derivative as LAT1 inhibitor and preparation method and application thereof | 中国药科大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-114031507-B | Synthesis method of o-aminobenzyl alcohol compound | 辽宁科信生物科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-4284782-A1 | AZA-CRYPTOPHANES, PROCESSES FOR PREPARATION THEREOF, AND THEIR USES | Université de Caen Normandie (FR) | 2023-12-06 | — | — | EP | disclosed |
| WO-2023219114-A1 | MRNA CAP ANALOG AND METHOD FOR PRODUCING SAME, METHOD FOR PRODUCING MRNA, AND KIT | ヤマサ醤油株式会社 | 2023-11-16 | — | — | WO | disclosed |
| US-4585588-A | ANTIDEPRESSANTS | BEECHAM GROUP P.L.C. (GB) | 1986-04-29 | — | — | US | disclosed |
| US-4518597-A | THROMBOSIS, ARTERIOSCLEROSIS, ANTITUMOR, ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1985-05-21 | — | — | US | disclosed |
| US-4504480-A | DIAZABENZOCYCLOHEPTAFLUORENE DERIVATRIVES, ANTIDEPRESSANTS | BEECHAM GROUP P.L.C. (GB) | 1985-03-12 | — | — | US | disclosed |
| EP-0093922-A2 | Benzoxazin-2-ones, their preparation and therapeutic agents containing these compounds | Dr. Karl Thomae GmbH (DE) | 1983-11-16 | — | — | EP | disclosed |
| EP-0088575-A2 | Pentacyclic compounds | BEECHAM GROUP PLC (GB) | 1983-09-14 | — | — | EP | disclosed |
| US-4268510-A | DEMETHANIZATION, METABOLISM, RUMEN | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-05-19 | — | — | US | disclosed |
| EP-0010348-A1 | Heterocyclic trichloromethyl derivatives, process for their preparation and their use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-04-30 | — | — | EP | disclosed |
| US-4101671-A | ANTIULCEROGENICS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-07-18 | — | — | US | disclosed |
| US-RE29628-E | ANTIULCER, SECRETOLYTICS, ANTITUSSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-09 | — | — | US | disclosed |
| US-3950393-A | ANTIULCER, ANTISECRETORY, ANTITUSSIVE AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12286407-B2 | Estrogen receptor beta ligands for the prevention and treatment of multiple sclerosis (MS) and other demyelinating, inflammatory and neurodegenerative diseases | ESR2, ESRRG, GPER1 | ALDH1A1 1027/4885CYP3A4 1246/4885MEN1 4465/4885 |
| US-20250223264-A1 | ESTROGEN RECEPTOR BETA LIGANDS FOR THE PREVENTION AND TREATMENT OF MULTIPLE SCLEROSIS (MS) AND OTHER DEMYELINATING, INFLAMMATORY AND NEURODEGENERATIVE DISEASES | ESR2, ESRRG, GPER1 | ALDH1A1 1027/4885CYP3A4 1246/4885MEN1 4465/4885 |
| US-20240124488-A1 | AZA-CRYPTOPHANES, PROCESSES FOR PREPARATION THEREOF, AND THEIR USES | TET3, AZI2, INMT | ALDH1A1 2601/4885CYP3A4 89/4885MEN1 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.