Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30189619 | 1.00 | CYP2D6 (0.51) | CYP2D6ALDH1A1CYP3A4ADRA1ATAAR1 | |
| SCHEMBL5058376 | 0.88 | ALDH1A1 (0.55) | ALDH1A1CYP3A4ADRA1ATAAR1MEN1 | |
| SCHEMBL3579011 | 0.85 | ALDH1A1 (0.52) | CYP2D6ALDH1A1CYP3A4ADRA1ATAAR1 | |
| SCHEMBL3377786 | 0.85 | ALDH1A1 (0.52) | ALDH1A1CYP3A4ADRA1ATAAR1MEN1 | |
| SCHEMBL7701522 | 0.83 | CYP2D6 (0.35) | CYP2D6ADRA1ATAAR1MEN1KMT2A | |
| SCHEMBL2019106 | 0.83 | TAAR1 (0.68) | ALDH1A1CYP3A4ADRA1ATAAR1MEN1 | |
| SCHEMBL22499932 | 0.82 | MEN1 (0.53) | ALDH1A1CYP3A4MEN1MAPTKMT2A | |
| SCHEMBL27848999 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CYP3A4ADRA1ATAAR1MEN1 | |
| SCHEMBL8680435 | 0.80 | ALDH1A1 (0.47) | ALDH1A1CYP3A4ADRA1ATAAR1MEN1 | |
| SCHEMBL1145887 | 0.79 | ADRA1A (0.68) | CYP2D6ADRA1ATAAR1IDO1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100432052-C | Synthetic method for methoxy indole | UNIV TIANJIN (CN) | 2008-11-12 | — | — | CN | claimed |
| CN-1944405-A | Synthetic method for methoxy indole | UNIV TIANJIN (CN) | 2007-04-11 | — | — | CN | claimed |
| US-12060347-B2 | Bicyclic heteroaryl substituted compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-13 | — | — | US | disclosed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |
| US-20210163465-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-06-03 | — | — | US | disclosed |
| US-20210163465-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-06-03 | — | — | US | disclosed |
| CN-112789259-A | Method for repairing structure | 昭和电工株式会社 | 2021-05-11 | — | — | CN | disclosed |
| CN-112752775-A | Radical polymerizable resin composition and structural repair material | 昭和电工株式会社 | 2021-05-04 | — | — | CN | disclosed |
| WO-2020203818-A1 | ASBESTOS DETECTING AGENT, ASBESTOS DETECTING KIT, AND ASBESTOS DETECTING METHOD | 広島県 | 2020-10-08 | — | — | WO | disclosed |
| EP-3484878-B1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2020-08-19 | — | — | EP | disclosed |
| WO-2020066364-A1 | RADICAL POLYMERIZABLE RESIN COMPOSITION AND STRUCTURE REPAIRING MATERIAL | 昭和電工株式会社 | 2020-04-02 | — | — | WO | disclosed |
| US-20190292176-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BISTOL MYERS SQUIBB COMPANY (US) | 2019-09-26 | — | — | US | disclosed |
| US-20190292176-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BISTOL MYERS SQUIBB COMPANY (US) | 2019-09-26 | — | — | US | disclosed |
| CN-109988093-A | The aminated compounds for inhibiting SSAO/VAP-1 and its application in medicine | 广东东阳光药业有限公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-109689647-A | The compound that bicyclic heteroaryl replaces | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |
| WO-2018013774-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-01-18 | — | — | WO | disclosed |
| CN-100432052-C | Synthetic method for methoxy indole | UNIV TIANJIN (CN) | 2008-11-12 | — | — | CN | disclosed |
| CN-1944405-A | Synthetic method for methoxy indole | UNIV TIANJIN (CN) | 2007-04-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12060347-B2 | Bicyclic heteroaryl substituted compounds | F2, F2RL3, F12 | CYP2D6 154/4885ALDH1A1 1598/4885CYP3A4 18/4885 |
| US-20190292176-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | F2, F2RL3, PF4 | CYP2D6 117/4885ALDH1A1 1618/4885CYP3A4 15/4885 |
| US-20210163465-A1 | BICYCLIC HETEROARYL SUBSTITUTED COMPOUNDS | F2, F2RL3, F12 | CYP2D6 154/4885ALDH1A1 1598/4885CYP3A4 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.