Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.48 |
| ▸ | AR | P10275 | 4/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631642 | 0.74 | PGR (0.55) | PGRARNR3C1NR3C2 | |
| SCHEMBL750088 | 0.73 | PDK2 (0.55) | PGR | |
| SCHEMBL3295805 | 0.70 | PGR (0.60) | PGRARNR3C1NR3C2 | |
| SCHEMBL3377467 | 0.70 | PGR (0.60) | PGRARNR3C1NR3C2 | |
| SCHEMBL3876801 | 0.69 | PGR (0.59) | PGRARNR3C1NR3C2 | |
| Brofoxine SCHEMBL61925 | 0.69 | PGR (0.59) | PGRARNR3C1NR3C2 | |
| SCHEMBL3380231 | 0.69 | PGR (0.59) | PGRARNR3C1NR3C2 | |
| SCHEMBL12649317 | 0.69 | PGR (0.59) | PGRARNR3C1NR3C2 | |
| SCHEMBL5633931 | 0.69 | RARB (0.39) | PGR | |
| SCHEMBL27735502 | 0.69 | BRD4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160304-A1 | AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-06-24 | — | — | US | disclosed |
| CN-101415709-A | Octahydro-pyrrolo [3, 4-b ] pyrrole derivatives and their use as histamine-3 receptor ligands | ABBOTT LAB (US) | 2009-04-22 | — | — | CN | disclosed |
| EP-1844768-A1 | AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2007-10-17 | — | — | EP | disclosed |
| CN-1145618-C | Cyclocarbamate derivatives as progesterone receptor modulators | �Ʒ� | 2004-04-14 | — | — | CN | disclosed |
| CN-1131856-C | Cyclothiocarbamate derivatives as progesterone receptor modulators | AMERICAN HOME PRODUCTS CORP. (US) | 2003-12-24 | — | — | CN | disclosed |
| CN-1349516-A | Cyclothiocarbamate derivatives as progesterone receptor modulators | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |
| CN-1349517-A | Cyclocarbamate derivatives as progesterone receptor modulators | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160304-A1 | AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR | NR3C2, AGTR1, AGTR2 | PGR 288/4885AR 17/4885NR3C1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.