Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31748788 | 0.87 | ALDH1A1 (0.82) | ALDH1A1KDM4ELMNAMAPTGAA | |
| SCHEMBL3486122 | 0.87 | ALDH1A1 (0.82) | ALDH1A1KDM4ELMNAMAPTGAA | |
| SCHEMBL30354951 | 0.85 | LMNA (0.63) | ALDH1A1KDM4ESMN1; SMN2LMNACYP2C19 | |
| SCHEMBL30354773 | 0.84 | SMN1; SMN2 (0.55) | ALDH1A1KDM4ESMN1; SMN2LMNACYP2C19 | |
| SCHEMBL30354961 | 0.84 | POLB (0.67) | ALDH1A1KDM4ESMN1; SMN2LMNACYP2C19 | |
| SCHEMBL29151336 | 0.84 | POLB (0.67) | ALDH1A1KDM4ESMN1; SMN2LMNACYP2C19 | |
| SCHEMBL2927789 | 0.81 | ALDH1A1 (0.83) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL1318958 | 0.81 | KDM4E (0.64) | ALDH1A1KDM4E | |
| SCHEMBL5252456 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL29882882 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278965-A1 | NOVEL CARBONOHYDRAZONOYL DICYANIDE COMPOUNDS COMPRISING 2 OR MORE ARYL OR HETEROARYL CONNECTED VIA LINKER AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2023-09-07 | — | — | US | disclosed |
| EP-4169916-A1 | CARBONOHYDRAZONOYL DICYANIDE COMPOUND INCLUDING AT LEAST TWO TYPES OF ARYL OR HETEROARYL LINKED BY NOVEL LINKER, AND USE THEREOF | Korea Institute of Science and Technology (KR) | 2023-04-26 | — | — | EP | disclosed |
| CN-115955968-A | Carbohydrazone acyldinitrile compounds comprising at least two aryl or heteroaryl groups connected by a novel linker and uses thereof | 韩国科学技术研究院 | 2023-04-11 | — | — | CN | disclosed |
| US-20100160304-A1 | AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-1844768-A1 | AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2007-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230278965-A1 | NOVEL CARBONOHYDRAZONOYL DICYANIDE COMPOUNDS COMPRISING 2 OR MORE ARYL OR HETEROARYL CONNECTED VIA LINKER AND USE THEREOF | AADAC, CBR3, MTCL3 | ALDH1A1 1104/4885KDM4E 2383/4885SMN1; SMN2 4675/4885 |
| US-20100160304-A1 | AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR | NR3C2, AGTR1, AGTR2 | ALDH1A1 1053/4885KDM4E 1109/4885SMN1; SMN2 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.