Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | MDM4 | O15151 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579964 | 0.92 | NPC1 (0.51) | NPC1RAB9AKMT2ATP53MEN1 | |
| SCHEMBL6580357 | 0.87 | NPC1 (0.55) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3381862 | 0.86 | POLB (0.56) | NPC1RAB9AKMT2ATP53MEN1 | |
| SCHEMBL6577537 | 0.86 | NPC1 (0.59) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6580254 | 0.83 | NR1H4 (0.53) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6580027 | 0.83 | F10 (0.66) | NPC1RAB9AKMT2ATP53MEN1 | |
| SCHEMBL28734392 | 0.82 | RAB9A (0.62) | NPC1RAB9AKMT2ATP53MEN1 | |
| SCHEMBL6580181 | 0.81 | MAPT (0.58) | NPC1RAB9AKMT2ATP53MEN1 | |
| SCHEMBL3414932 | 0.81 | NPC1 (0.63) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6579947 | 0.80 | NPC1 (0.67) | NPC1RAB9AKMT2ATP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002075-A1 | METHODS FOR PREPARING AMIDE DERIVATIVES | PHARMACOSTECH CO., LTD. (KR) | 2010-01-07 | — | — | WO | disclosed |
| WO-2010002075-A1 | METHODS FOR PREPARING AMIDE DERIVATIVES | PHARMACOSTECH CO., LTD. (KR) | 2010-01-07 | — | — | WO | disclosed |