Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372951 | 0.88 | KMT2A (0.69) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3378777 | 0.87 | RAB9A (0.63) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6580357 | 0.82 | NPC1 (0.55) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3381862 | 0.82 | POLB (0.56) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3377996 | 0.81 | NPC1 (0.59) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3377229 | 0.80 | KCNMA1 (0.60) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL8337442 | 0.79 | NPC1 (0.80) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6580254 | 0.78 | NR1H4 (0.53) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6580027 | 0.78 | F10 (0.66) | NPC1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6580151 | 0.78 | NR1H4 (0.48) | NPC1MEN1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002075-A1 | METHODS FOR PREPARING AMIDE DERIVATIVES | PHARMACOSTECH CO., LTD. (KR) | 2010-01-07 | — | — | WO | disclosed |
| WO-2010002075-A1 | METHODS FOR PREPARING AMIDE DERIVATIVES | PHARMACOSTECH CO., LTD. (KR) | 2010-01-07 | — | — | WO | disclosed |