Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622015 | 0.83 | ADORA3 (0.37) | MAOBMAOAADORA3ADORA2AADORA1 | |
| SCHEMBL514334 | 0.74 | CA12 (0.35) | — | |
| SCHEMBL767227 | 0.74 | ALDH1A1 (0.40) | MAOBMAOAADORA3ADORA2AADORA1 | |
| SCHEMBL5310084 | 0.74 | NPC1 (0.39) | ALDH1A1CYP1A2HPGDHSD17B10 | |
| SCHEMBL3090062 | 0.74 | NPC1 (0.37) | ADORA3ALDH1A1 | |
| SCHEMBL315654 | 0.74 | CYP2A6 (0.47) | MAOBADORA3ADORA2AADORA1CYP2A6 | |
| SCHEMBL3093044 | 0.70 | CYP1A2 (0.33) | CYP2A6CYP1A2 | |
| SCHEMBL767336 | 0.70 | ADORA3 (0.47) | ADORA3ADORA2AADORA1CYP2A6ALDH1A1 | |
| SCHEMBL2517288 | 0.70 | ALDH1A1 (0.46) | ADORA1CYP2A6ALDH1A1CYP1A2HPGD | |
| SCHEMBL6294406 | 0.70 | NUDT1 (0.37) | CYP2A6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401738-A | Angiotensin antagonist, hypotensive, aldosteronism, cardiac insufficiency | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER (DE) | 1995-03-28 | — | — | US | claimed |
| CN-109311844-B | Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component | 东曹株式会社 | 2021-07-20 | — | — | CN | disclosed |
| CN-112912372-A | Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element | 东曹株式会社 | 2021-06-04 | — | — | CN | disclosed |
| WO-2020085319-A1 | CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT | 東ソー株式会社 | 2020-04-30 | — | — | WO | disclosed |
| WO-2019163959-A1 | CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT | 東ソー株式会社 | 2019-08-29 | — | — | WO | disclosed |
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| EP-1364946-B1 | ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2010-11-24 | — | — | EP | disclosed |
| EP-2186410-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-05-19 | — | — | EP | disclosed |
| EP-0595151-A2 | Imidazopyridine derivates as antagonists of angiotensin II | MERCK PATENT GmbH (DE) | 1994-05-04 | — | — | EP | disclosed |
| EP-0589201-A1 | Di- and triazindeones | MERCK PATENT GmbH (DE) | 1994-03-30 | — | — | EP | disclosed |
| CN-1082542-A | Benzimidizole derivatives | MERCK PATENT GMBH (DE) | 1994-02-23 | — | — | CN | disclosed |
| CN-1082045-A | Imidazopyridine | MERCK PATENT GMBH (DE) | 1994-02-16 | — | — | CN | disclosed |
| EP-0574787-A2 | Benzimidazole derivatives as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |
| EP-0574846-A2 | Imidazopyridines as angiotensin II antagonistes | MERCK PATENT GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |
| EP-0564960-A1 | Imidazopyridines as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-10-13 | — | — | EP | disclosed |
| US-5242928-A | Angiotensin II antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-07 | — | — | US | disclosed |
| EP-0547514-A2 | Imidazopyridine derivatives with angiotensin-II antagonist properties | MERCK PATENT GmbH (DE) | 1993-06-23 | — | — | EP | disclosed |
| EP-0480795-A1 | Benzofuran derivatives, procedure of their preparation, novel intermediates obtained, and their application as pesticides | ROUSSEL-UCLAF (FR) | 1992-04-15 | — | — | EP | disclosed |