SCHEMBL3378475

SCHEMBL3378475

CC(C)c1ccccc1[SiH3]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.50
GABRB2 P47870 2/20 0.50
GABRG2 P18507 2/20 0.46
GABRB3 P28472 2/20 0.46
FAAH O00519 2/20 0.46
LMNA P02545 2/20 0.46
TSHR P16473 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46
GABRB1 P18505 1/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46
HTR2C P28335 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
HTR2B P41595 1/20 0.46
GABRA2 P47869 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10884302 0.95 GABRA1 (0.46) GABRA1GABRB2GABRG2GABRB3FAAH
SCHEMBL68911 0.79 GABRA1 (0.36) GABRA1GABRB2GABRG2GABRB3FAAH
SCHEMBL28598232 0.79 GABRA1 (0.36) GABRA1GABRB2GABRG2GABRB3FAAH
SCHEMBL66162 0.78 GABRA1 (0.63) GABRA1GABRB2GABRG2GABRB3FAAH
SCHEMBL29429205 0.78 GABRA1 (0.63) GABRA1GABRB2GABRG2GABRB3FAAH
SCHEMBL2744517 0.77 GABRA1 (0.46) GABRA1GABRB2GABRG2GABRB3FAAH
Water SCHEMBL10586200 0.76 GABRA1 (0.60) GABRA1GABRB2GABRG2GABRB3FAAH
SCHEMBL6203906 0.76 GABRA1 (0.60) GABRA1GABRB2GABRG2GABRB3FAAH
Water SCHEMBL2581333 0.76 GABRA1 (0.60) GABRA1GABRB2GABRG2GABRB3FAAH
Ammonia Solution, Strong SCHEMBL7550582 0.76 GABRA1 (0.60) GABRA1GABRB2GABRG2GABRB3FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114920768-A Preparation method and application of tert-butyl substituted dihydrosilane and chiral silane 深圳湾实验室 2022-08-19 CN claimed
CN-115716847-A Preparation method of B, si-bimetal reagent 苏州大学 2023-02-28 CN disclosed
CN-114920768-A Preparation method and application of tert-butyl substituted dihydrosilane and chiral silane 深圳湾实验室 2022-08-19 CN disclosed
CN-109563186-B Method for producing modified conjugated diene polymer and method for producing polymer composition 住友化学株式会社 2022-04-15 CN disclosed
CN-114207038-A Resin composition, method for producing cured product, patterned cured product, interlayer insulating film, covercoat, surface protective film, and electronic component 艾曲迪微系统股份有限公司 2022-03-18 CN disclosed
CN-113748134-A Conjugated diene copolymer and method for producing conjugated diene copolymer 瑞住合成橡胶株式会社 2021-12-03 CN disclosed
US-9970103-B2 Film deposition material, sealing film using the same and use thereof TOSOH CORPORATION (JP) 2018-05-15 US disclosed
EP-2855018-B1 PROCESS OF PREPARATION OF A CATALYST COMPRISING A GROUP VIII METAL AND SILICON AND PROCESS OF SELECTIVE HYDROGENATION USING THAT CATALYST IFP ENERGIES NOW (FR) 2017-10-18 EP disclosed
US-9695095-B2 Process for preparing a catalyst based on a group VIII metal and containing silicon, and a process of selective hydrogenation implementing said catalyst IFP Energies Nouvelles (FR) 2017-07-04 US disclosed
US-20160326642-A1 FILM DEPOSITION MATERIAL, SEALING FILM USING THE SAME AND USE THEREOF TOSOH CORPORATION (JP) 2016-11-10 US disclosed
US-20150141718-A1 PROCESS FOR PREPARING A CATALYST BASED ON A GROUP VIII METAL AND CONTAINING SILICON, AND A PROCESS OF SELECTIVE HYDROGENATION IMPLEMENTING SAID CATALYST IFP Energies Nouvelles (FR) 2015-05-21 US disclosed
EP-2855018-A1 PROCESS FOR PREPARING A CATALYST BASED ON A GROUP VIII METAL AND CONTAINING SILICON AND SELECTIVE HYDROGENATION PROCESS USING SAID CATALYST IFP Energies nouvelles (FR) 2015-04-08 EP disclosed
US-20140219903-A1 FILM DEPOSITION MATERIAL, SEALING FILM USING THE SAME AND USE THEREOF TOSOH CORPORATION (JP) 2014-08-07 US disclosed
WO-2013175085-A1 PROCESS FOR PREPARING A CATALYST BASED ON A GROUP VIII METAL AND CONTAINING SILICON AND SELECTIVE HYDROGENATION PROCESS USING SAID CATALYST IFP Energies Nouvelles (FR) 2013-11-28 WO disclosed
EP-1452549-B1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO LTD (JP) 2010-11-17 EP disclosed
US-7629419-B2 Process for producing modified polymer, apparatus for producing modified polymer, and modified polymer SEKISUI CHEMICAL CO., LTD. (JP) 2009-12-08 US disclosed
US-20050053792-A1 High purity; using supercritical fluid; high temperature; high pressure; polyolefins; interface film for glass; ceramic binder SEKISUI CHEMICAL CO., LTD. (JP) 2005-03-10 US disclosed
EP-1452549-A1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO., LTD. (JP) 2004-09-01 EP disclosed
US-6471955-B1 POLYSTYRENES AS PREFERENTIAL TIME-RELEASE AGENTS OR CARRIERS OF PROSTAGLANDINS SUCH AS MISOPROSTOL USED FOR PREVENTION OF PEPTIC ULCERS PHARMACIA CORPORATION 2002-10-29 US disclosed
WO-1998044952-A1 pH-SELECTIVE DELIVERY SYSTEM USING CROSS-LINKED POLYMERIC RESINS AS VEHICLES MONSANTO COMPANY (US) 1998-10-15 WO disclosed