SCHEMBL28598232

SCHEMBL28598232

CC(F)c1ccccc1[SiH3]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
TSHR P16473 2/20 0.32
FAAH O00519 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
PTGS1 P23219 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
HTR2B P41595 1/20 0.32
GABRA2 P47869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10429859 0.81 GABRA1 (0.43) GABRA1GABRB2TSHRFAAHCA1
SCHEMBL3406061 0.79 TRPA1 (0.30)
SCHEMBL3378475 0.79 GABRA1 (0.50) GABRA1GABRB2TSHRFAAHCA1
SCHEMBL68911 0.75 GABRA1 (0.36) GABRA1GABRB2TSHRFAAHCA1
SCHEMBL10884302 0.75 GABRA1 (0.46) GABRA1GABRB2TSHRFAAHCA1
SCHEMBL4547934 0.74 GABRA1 (0.50) GABRA1GABRB2TSHRFAAHCA1
SCHEMBL235044 0.73 TSHR (0.35) GABRA1GABRB2TSHRCYP3A4ESR1
SCHEMBL17297902 0.72 ESR1 (0.52) GABRA1GABRB2TSHRCA1CA2
SCHEMBL19640328 0.72 GABRA1 (0.37) GABRA1GABRB2TSHRFAAHCA1
SCHEMBL2267939 0.71 HTR2A (0.44) GABRA1GABRB2TSHRFAAHCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113122683-B High-wear-resistance alloy steel for linear guide rail and preparation method thereof 江阴大手印精密材料科技发展有限公司 2022-09-30 CN claimed
CN-113122683-A High-wear-resistance alloy steel for linear guide rail and preparation method thereof 江阴大手印精密材料科技发展有限公司 2021-07-16 CN claimed
CN-113122683-B High-wear-resistance alloy steel for linear guide rail and preparation method thereof 江阴大手印精密材料科技发展有限公司 2022-09-30 CN disclosed
CN-113122683-A High-wear-resistance alloy steel for linear guide rail and preparation method thereof 江阴大手印精密材料科技发展有限公司 2021-07-16 CN disclosed