SCHEMBL3378641

SCHEMBL3378641

CC(C)=C[SiH2]c1ccc(Br)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.39
TSHR P16473 2/20 0.37
NPC1 O15118 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NFKB1 P19838 1/20 0.37
RAB9A P51151 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
CYP2A6 P11509 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
ALDH1A1 P00352 2/20 0.35
ALOX15 P16050 1/20 0.35
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL758547 0.88
SCHEMBL11360965 0.77 NPC1 (0.37) NPC1SMN1; SMN2RAB9ACYP2A6MEN1
SCHEMBL10546504 0.74
SCHEMBL11352866 0.74 NOS3 (0.42) NOS1TSHRCA1CA2
SCHEMBL11355626 0.72 NOS1 (0.46) NOS1SMN1; SMN2CA1CA2ALDH1A1
SCHEMBL6114211 0.70
Potassium Ion SCHEMBL11351404 0.70 CA2 (0.41) CA1CA2MAPT
SCHEMBL28753437 0.69 ENPP2 (0.35) NPC1SMN1; SMN2RAB9AALDH1A1MEN1
SCHEMBL4383263 0.68 CCR1 (0.37)
SCHEMBL28536424 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020116367-A1 POLYBUTADIENE AND METHOD FOR PRODUCING SAME 宇部興産株式会社 2020-06-11 WO disclosed
EP-1452549-B1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO LTD (JP) 2010-11-17 EP disclosed
US-7629419-B2 Process for producing modified polymer, apparatus for producing modified polymer, and modified polymer SEKISUI CHEMICAL CO., LTD. (JP) 2009-12-08 US disclosed
US-20050053792-A1 High purity; using supercritical fluid; high temperature; high pressure; polyolefins; interface film for glass; ceramic binder SEKISUI CHEMICAL CO., LTD. (JP) 2005-03-10 US disclosed
EP-1452549-A1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO., LTD. (JP) 2004-09-01 EP disclosed