Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.33 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634857 | 0.83 | NOTUM (0.42) | NOTUMHTR3AADRB2ADRB1GAA | |
| SCHEMBL27680544 | 0.76 | ADRB2 (0.37) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10616182 | 0.74 | ALDH1A1 (0.39) | NOTUMHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9852678 | 0.73 | ADRB2 (0.38) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL27680558 | 0.73 | ADRB2 (0.41) | NOTUMHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL1263100 | 0.73 | IDO1 (0.37) | NOTUMHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL24616502 | 0.72 | TSHR (0.43) | NOTUMHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2957239 | 0.72 | NOTUM (0.38) | NOTUMHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11602314 | 0.71 | NOTUM (0.40) | NOTUMHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9748215 | 0.71 | ALDH1A1 (0.36) | NOTUMHTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968578-A2 | POLYMORPHS AND AMORPHOUS FORMS OF 5-AMINO-l-[2,6- DICHLORO-4-(TRIFLUOROMETHYL)PHENYL]-4- [(TRIFLUOROMETHYL)SULFINYL]-IH-PYRAZOLE-3-CARBONITRILE | MAKHTESHIM CHEMICAL WORKS LIMITED (IL) | 2008-09-17 | — | — | EP | claimed |
| WO-2007069254-A2 | POLYMORPHS AND AMORPHOUS FORMS OF 5-AMINO-l-[2,6- DICHLORO-4-(TRIFLUOROMETHYL)PHENYL]-4- [(TRIFLUOROMETHYL)SULFINYL]-IH-PYRAZOLE-3-CARBONITRILE | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 2007-06-21 | — | — | WO | claimed |
| WO-2010049789-A1 | PROCESS FOR THE SYNTHESIS OF FIPRONIL | DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNICK (DE) | 2010-05-06 | — | — | WO | disclosed |