Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 10/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.31 |
| ▸ | HTR3A | P46098 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855792 | 0.80 | TP53 (0.36) | NOTUMRAPGEF4CYP2C9CYP2C19P2RX7 | |
| SCHEMBL11602314 | 0.77 | NOTUM (0.40) | NOTUMHTR3AIDO1HTR3EHTR3B | |
| SCHEMBL28785582 | 0.75 | P2RX7 (0.33) | NOTUMRAPGEF4CYP2C9CYP2C19P2RX7 | |
| SCHEMBL29702062 | 0.75 | P2RX7 (0.33) | NOTUMRAPGEF4CYP2C9CYP2C19P2RX7 | |
| SCHEMBL1263100 | 0.75 | IDO1 (0.37) | NOTUMRAPGEF4HTR3AIDO1HTR3E | |
| SCHEMBL3379043 | 0.72 | NOTUM (0.39) | NOTUMHTR3AIDO1HTR3EHTR3B | |
| SCHEMBL7894304 | 0.72 | TP53 (0.34) | NOTUMRAPGEF4CYP2C9CYP2C19P2RX7 | |
| SCHEMBL9723067 | 0.72 | RAPGEF4 (0.33) | NOTUMRAPGEF4CYP2C9CYP2C19P2RX7 | |
| SCHEMBL15517270 | 0.72 | RAPGEF4 (0.42) | NOTUMRAPGEF4CYP2C9CYP2C19P2RX7 | |
| SCHEMBL1768795 | 0.72 | CYP3A4 (0.50) | NOTUMHTR3AIDO1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8298830-B2 | Organic materials able to detect analytes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-10-30 | — | — | US | disclosed |
| US-20100310424-A1 | ORGANIC MATERIALS ABLE TO DETECT ANALYTES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-12-09 | — | — | US | disclosed |
| US-7759127-B2 | Organic materials able to detect analytes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-20 | — | — | US | disclosed |
| US-7700366-B2 | Fluorescent, semi-conductive polymers, and devices comprising them | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-04-20 | — | — | US | disclosed |
| US-20060073607-A1 | Organic materials able to detect analytes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-04-06 | — | — | US | disclosed |
| US-20050196775-A1 | Fluorescent, semi-conductive polymers, and devices comprising them | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-09-08 | — | — | US | disclosed |
| WO-2005073338-A2 | FLUORESCENT, SEMI-CONDUCTIVE POLYMERS, AND DEVICES COMPRISING THEM | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-08-11 | — | — | WO | disclosed |