Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 9/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23416481 | 0.81 | GAA (0.35) | — | |
| SCHEMBL18827172 | 0.76 | PDE2A (0.36) | NOTUM | |
| SCHEMBL11602223 | 0.75 | NOTUM (0.44) | IDO1NOTUMHTR3EHTR3BHTR3A | |
| SCHEMBL1263960 | 0.75 | NOTUM (0.50) | IDO1NOTUMHTR3EHTR3BHTR3A | |
| SCHEMBL2957239 | 0.75 | NOTUM (0.38) | IDO1NOTUMHTR3EHTR3BHTR3A | |
| SCHEMBL24616502 | 0.75 | TSHR (0.43) | IDO1NOTUMHTR3EHTR3BHTR3A | |
| SCHEMBL11602314 | 0.73 | NOTUM (0.40) | IDO1NOTUMHTR3EHTR3BHTR3A | |
| SCHEMBL3379043 | 0.73 | NOTUM (0.39) | IDO1NOTUMHTR3EHTR3BHTR3A | |
| SCHEMBL2986241 | 0.70 | NOTUM (0.46) | IDO1NOTUMHTR3EHTR3BHTR3A | |
| SCHEMBL9628331 | 0.70 | ALDH1A1 (0.45) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9647218-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2017-05-09 | — | — | US | disclosed |
| EP-1955990-B1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVES | TORAY FINECHEMICALS CO LTD (JP) | 2012-08-22 | — | — | EP | disclosed |
| US-7893306-B2 | Process for production of biphenyl derivatives | TORAY FINE CHEMICALS CO., LTD. (JP) | 2011-02-22 | — | — | US | disclosed |
| US-20080319238-A1 | Process for Production of Biphenyl Derivatives | Hayashi, Tamio (JP) | 2008-12-25 | — | — | US | disclosed |
| EP-1955990-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVES | Toray Fine Chemicals Co., Ltd. (JP) | 2008-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319238-A1 | Process for Production of Biphenyl Derivatives | CYP2F1, CYP4B1, CYP4F2 | IDO1 1014/4885NOTUM 631/4885HTR3E 2721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.