SCHEMBL3379045

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3379044	1.00	TET2 (0.52)	TET2KDM4AKDM4CKDM2ATET3
	SCHEMBL11712215	0.82	KMT2A (0.50)	TET2KDM4AKDM4CKDM2ATET3
	SCHEMBL3883135	0.82	KMT2A (0.50)	TET2KDM4AKDM4CKDM2ATET3
	SCHEMBL3377870	0.82	TET2 (0.43)	TET2KDM4AKDM4CKDM2ATET3
	SCHEMBL3377867	0.82	TET2 (0.43)	TET2KDM4AKDM4CKDM2ATET3
	SCHEMBL11711858	0.80	GPR84 (0.33)	TET2KDM4AKDM4CKDM2ATET3
	SCHEMBL4781073	0.78	TET2 (0.48)	TET2KDM4AKDM4CKDM2ATET3
	SCHEMBL4713126	0.78	TET2 (0.48)	TET2KDM4AKDM4CKDM2ATET3
	SCHEMBL7628611	0.77	CYP1A2 (0.52)	TET2KDM4AKDM4CKDM2ATET3
	SCHEMBL7628614	0.77	CYP1A2 (0.52)	TET2KDM4AKDM4CKDM2ATET3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.