SCHEMBL3379257

SCHEMBL3379257

C=C(C(=O)O)C(C)C1(Cc2ccccc2)COC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.36
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
XBP1 P17861 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.33
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CNR2 P34972 1/20 0.33
CHRM2 P08172 3/20 0.33
CHRM4 P08173 3/20 0.33
CHRM5 P08912 3/20 0.33
CHRM1 P11229 3/20 0.33
CHRM3 P20309 3/20 0.33
OPRL1 P41146 2/20 0.32
OPRM1 P35372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3376617 0.83 KDM4E (0.33) LMNAMAPTSMN1; SMN2NPSR1XBP1
SCHEMBL3376033 0.82 POLB (0.36) TSHRCNR2OPRM1MEN1KMT2A
SCHEMBL782172 0.77
SCHEMBL3379280 0.75 ALDH1A1 (0.38) HPGDLMNAMAPTSMN1; SMN2NPSR1
SCHEMBL3378705 0.74
SCHEMBL17420847 0.72
SCHEMBL780494 0.71
SCHEMBL18297873 0.71
SCHEMBL17420842 0.70 ACE2 (0.32) TSHRALDH1A1MEN1KMT2A
SCHEMBL5028984 0.67 MAOA (0.43) OPRL1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8361376-B2 Process of making a three-dimensional object CMET INC. (JP) 2013-01-29 US disclosed
US-20100104804-A1 Three-Dimensional Object Having Smoothed Fabricated Edge Surface CMET INC. (JP) 2010-04-29 US disclosed