SCHEMBL33793

SCHEMBL33793

CC1=C(C)[C@H]2[C@H](Cc3ccccc3)NC(=O)[C@]23[C@H](O)/C=C/[C@](C)(O)C[C@@H](C)C/C=C/[C@H]3[C@@H]1O

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.59
NR0B1 P51843 1/20 0.45
NPC1 O15118 2/20 0.40
LMNA P02545 1/20 0.40
SLC2A1 P11166 1/20 0.40
SLC2A2 P11168 1/20 0.40
SLC2A3 P11169 1/20 0.40
SLC2A4 P14672 1/20 0.40
MAPK1 P28482 1/20 0.40
RAB9A P51151 1/20 0.40
SLC2A9 Q9NRM0 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HIF1A Q16665 1/20 0.40
PAX8 Q06710 1/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CCR5 P51681 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29745674 1.00 ADORA3 (0.59) ADORA3NR0B1NPC1LMNASLC2A1
SCHEMBL33772 0.83 ADORA3 (0.80) ADORA3NR0B1NPC1LMNASLC2A1
SCHEMBL29408780 0.82 ADORA3 (0.60) ADORA3NR0B1NPC1LMNASLC2A1
SCHEMBL33787 0.82 ADORA3 (0.60) ADORA3NR0B1NPC1LMNASLC2A1
SCHEMBL33816 0.82 ADORA3 (0.60) ADORA3NR0B1NPC1LMNASLC2A1
SCHEMBL33544 0.81 ADORA3 (0.56) ADORA3NR0B1NPC1LMNASLC2A1
SCHEMBL33777 0.76 NR0B1 (0.74) ADORA3NR0B1NPC1LMNASLC2A1
SCHEMBL33708 0.75 ADORA3 (1.00) ADORA3NR0B1NPC1LMNASLC2A1
SCHEMBL30119602 0.75 ADORA3 (1.00) ADORA3NR0B1NPC1LMNASLC2A1
SCHEMBL33778 0.73 ADORA3 (0.77) ADORA3NR0B1NPC1LMNASLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090062904-A1 STENT COATING ICON INTERVENTIONAL SYSTEMS, INC. 2009-03-05 US claimed
EP-0429585-A4 CYTOCHALASIN COMPOSITIONS AND THERAPEUTIC METHODS 1992-03-25 EP claimed
EP-0429585-A1 CYTOCHALASIN COMPOSITIONS AND THERAPEUTIC METHODS SYRACUSE UNIVERSITY (US) 1991-06-05 EP claimed
WO-1990013293-A1 CYTOCHALASIN COMPOSITIONS AND THERAPEUTIC METHODS SYRACUSE UNIVERSITY (US) 1990-11-15 WO claimed
US-20260070124-A1 METHOD FOR FORMING A TUBE MIRUS LLC (US) 2026-03-12 US disclosed
EP-4404878-A1 COATING FOR REFRACTORY METAL ALLOY MiRus LLC (US) 2024-07-31 EP disclosed
EP-1858440-B1 IMPROVED METAL ALLOYS FOR MEDICAL DEVICE MIRUS LLC (US) 2024-04-24 EP disclosed
US-20230390454-A1 STENT DEVICE FOR SPINAL FUSION MIRUS LLC 2023-12-07 US disclosed
US-11766506-B2 Stent device for spinal fusion MIRUS LLC (US) 2023-09-26 US disclosed
EP-3316826-B1 MOLYBDENUM ALLOYS FOR MEDICAL DEVICES MIRUS LLC (US) 2023-04-19 EP disclosed
WO-2023048840-A1 COATING FOR REFRACTORY METAL ALLOY MIRUS LLC (US) 2023-03-30 WO disclosed
EP-3055438-B1 A METHOD OF FORMING A MEDICAL DEVICE AND A MEDICAL DEVICE IN THE FORM OF AN ORTHODONTICS DEVICE MIRUS LLC (US) 2023-03-15 EP disclosed
EP-0975340-A2 THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 2000-02-02 EP disclosed
US-5981568-A ADMINISTERING TO A PROCEDURALLY TRAUMATIZED MAMMALIAN BLOOD VESSEL A SUSTAINED RELEASE DOSAGE FORM COMPRISING MICROPARTICLES COMPRISING TAXOL OR AN ANALOG THEREOF NEORX CORPORATION (US) 1999-11-09 US disclosed
WO-1998043618-A9 USE OF CYTOSKELETAL INHIBITORS FOR THE PREVENTION OF RESTENOSIS NEORX CORP (US) 1999-04-22 WO disclosed
WO-1998043618-A2 USE OF CYTOSKELETAL INHIBITORS FOR THE PREVENTION OF RESTENOSIS NEORX CORPORATION (US) 1998-10-08 WO disclosed
US-5811447-A Therapeutic inhibitor of vascular smooth muscle cells NEORX CORPORATION (US) 1998-09-22 US disclosed
US-5733925-A ADMINISTERING TAXOL TREATING CARDIOVASCULAR DISORDER NEORX CORPORATION (US) 1998-03-31 US disclosed
EP-0809515-A1 THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1997-12-03 EP disclosed
WO-1996025176-A1 THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1996-08-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070124-A1 METHOD FOR FORMING A TUBE NIT2, NFE2L2, DUOX2 ADORA3 3123/4885NR0B1 2547/4885NPC1 2580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.