SCHEMBL33778

SCHEMBL33778

CC(=O)O[C@@H]1/C=C/[C@](C)(O)C[C@@H](C)C/C=C/[C@H]2[C@H](O)[C@@](C)(O)[C@@H](C)[C@H]3[C@H](Cc4ccccc4)NC(=O)[C@@]312

nearest known ligand 0.77

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.77
NR0B1 P51843 1/20 0.60
CCR5 P51681 1/20 0.50
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NPC1 O15118 2/20 0.38
LMNA P02545 1/20 0.38
SLC2A1 P11166 1/20 0.38
SLC2A2 P11168 1/20 0.38
SLC2A3 P11169 1/20 0.38
SLC2A4 P14672 1/20 0.38
MAPK1 P28482 1/20 0.38
RAB9A P51151 1/20 0.38
SLC2A9 Q9NRM0 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
PAX8 Q06710 1/20 0.38
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29408780 0.89 ADORA3 (0.60) ADORA3NR0B1CCR5MEN1KMT2A
SCHEMBL33787 0.89 ADORA3 (0.60) ADORA3NR0B1CCR5MEN1KMT2A
SCHEMBL33816 0.89 ADORA3 (0.60) ADORA3NR0B1CCR5MEN1KMT2A
SCHEMBL30119602 0.87 ADORA3 (1.00) ADORA3NR0B1CCR5MEN1KMT2A
SCHEMBL33708 0.87 ADORA3 (1.00) ADORA3NR0B1CCR5MEN1KMT2A
SCHEMBL33544 0.77 ADORA3 (0.56) ADORA3NR0B1CCR5MEN1KMT2A
SCHEMBL33772 0.75 ADORA3 (0.80) ADORA3NR0B1CCR5MEN1KMT2A
Cytochalasin D SCHEMBL12648577 0.75 NR0B1 (1.00) ADORA3NR0B1CCR5MEN1KMT2A
Cytochalasin D SCHEMBL31734099 0.75 NR0B1 (1.00) ADORA3NR0B1CCR5MEN1KMT2A
Cytochalasin D SCHEMBL33528 0.75 NR0B1 (1.00) ADORA3NR0B1CCR5MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090062904-A1 STENT COATING ICON INTERVENTIONAL SYSTEMS, INC. 2009-03-05 US claimed
US-20260070124-A1 METHOD FOR FORMING A TUBE MIRUS LLC (US) 2026-03-12 US disclosed
EP-4404878-A1 COATING FOR REFRACTORY METAL ALLOY MiRus LLC (US) 2024-07-31 EP disclosed
EP-1858440-B1 IMPROVED METAL ALLOYS FOR MEDICAL DEVICE MIRUS LLC (US) 2024-04-24 EP disclosed
US-20240024542-A1 METAL ALLOYS FOR METAL DEVICES MIRUS LLC 2024-01-25 US disclosed
US-20230390454-A1 STENT DEVICE FOR SPINAL FUSION MIRUS LLC 2023-12-07 US disclosed
US-11779685-B2 Metal alloys for medical devices MIRUS LLC (US) 2023-10-10 US disclosed
US-11766506-B2 Stent device for spinal fusion MIRUS LLC (US) 2023-09-26 US disclosed
EP-3316826-B1 MOLYBDENUM ALLOYS FOR MEDICAL DEVICES MIRUS LLC (US) 2023-04-19 EP disclosed
WO-2023048840-A1 COATING FOR REFRACTORY METAL ALLOY MIRUS LLC (US) 2023-03-30 WO disclosed
WO-1998043618-A2 USE OF CYTOSKELETAL INHIBITORS FOR THE PREVENTION OF RESTENOSIS NEORX CORPORATION (US) 1998-10-08 WO disclosed
US-5811447-A Therapeutic inhibitor of vascular smooth muscle cells NEORX CORPORATION (US) 1998-09-22 US disclosed
EP-0702557-A4 THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORP (US) 1998-06-03 EP disclosed
US-5733925-A ADMINISTERING TAXOL TREATING CARDIOVASCULAR DISORDER NEORX CORPORATION (US) 1998-03-31 US disclosed
EP-0809515-A1 THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1997-12-03 EP disclosed
WO-1996025176-A1 THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1996-08-22 WO disclosed
EP-0702557-A1 THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1996-03-27 EP disclosed
EP-0681475-A1 THERAPEUTIC INHIBITORS OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1995-11-15 EP disclosed
WO-1994026291-A1 THERAPEUTIC INHIBITOR OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1994-11-24 WO disclosed
WO-1994016706-A1 THERAPEUTIC INHIBITORS OF VASCULAR SMOOTH MUSCLE CELLS NEORX CORPORATION (US) 1994-08-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070124-A1 METHOD FOR FORMING A TUBE NIT2, NFE2L2, DUOX2 ADORA3 3123/4885NR0B1 2547/4885CCR5 4324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.