Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3380146

O=C([O-])C(F)(F)F.O=C([O-])C(F)(F)F.O=C([O-])C(F)(F)F.O=C([O-])C(F)(F)F.O=C1OC2(c3ccccc31)c1cc(F)c(O)c([Hg+2])c1Oc1c2cc(F)c(O)c1[Hg+2]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
TDP1 Q9NUW8 4/20 0.50
RECQL P46063 2/20 0.50
BLM P54132 2/20 0.50
ACE2 Q9BYF1 2/20 0.50
PRMT1 Q99873 2/20 0.50
USP2 O75604 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
THRB P10828 1/20 0.50
CDK2 P24941 1/20 0.50
CHAT P28329 1/20 0.50
BLVRB P30043 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
GNG2 P59768 1/20 0.48
GNB1 P62873 1/20 0.48
MAPT P10636 6/20 0.46
FTO Q9C0B1 2/20 0.46
HTT P42858 2/20 0.46
CYP2C19 P33261 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL3376242 0.84 GNG2 (0.60) MEN1KMT2ATDP1RECQLBLM
SCHEMBL1942341 0.79 MEN1 (0.61) MEN1KMT2ATDP1RECQLBLM
SCHEMBL7960302 0.74 MEN1 (0.55) MEN1KMT2ATDP1RECQLBLM
SCHEMBL3656975 0.72 MEN1 (0.50) MEN1KMT2ATDP1RECQLBLM
SCHEMBL14905188 0.71 MAPT (0.55) MEN1KMT2ATDP1RECQLBLM
SCHEMBL16303146 0.71 MAPT (0.55) MEN1KMT2ATDP1RECQLBLM
SCHEMBL16984048 0.68 MAPT (0.56) MEN1KMT2ATDP1RECQLBLM
SCHEMBL408340 0.68 MAPT (0.64) MEN1KMT2ATDP1RECQLBLM
SCHEMBL29367262 0.68 MAPT (0.64) MEN1KMT2ATDP1RECQLBLM
SCHEMBL30218785 0.68 MAPT (0.64) MEN1KMT2ATDP1RECQLBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2029673-B1 IMPROVED PHOTOSTABLE FRET-COMPETENT BIARSENICAL-TETRACYSTEINE PROBES BASED ON FLUORINATED FLUORESCEINS MAX PLANCK GESELLSCHAFT (DE) 2010-11-17 EP disclosed
US-20090098596-A1 PHOTOSTABLE FRET-COMPETENT BIARSENICAL-TETRACYSTEINE PROBES BASED ON FLUORINATED FLUORESCEINS MAX-PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2009-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098596-A1 PHOTOSTABLE FRET-COMPETENT BIARSENICAL-TETRACYSTEINE PROBES BASED ON FLUORINATED FLUORESCEINS TTR, TCOF1, HLCS MEN1 673/4885KMT2A 4492/4885TDP1 1445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.