Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | AANAT | Q16613 | 1/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.32 |
| ▸ | YAP1 | P46937 | 1/20 | 0.32 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.32 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28383270 | 0.89 | TSHR (0.40) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL10866810 | 0.81 | HDAC3 (0.41) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL10067925 | 0.80 | TDP1 (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL559906 | 0.77 | ALDH1A1 (0.56) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL16853223 | 0.76 | ALDH1A1 (0.48) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL16853220 | 0.76 | ALDH1A1 (0.55) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL7135125 | 0.76 | — | — | |
| SCHEMBL31026918 | 0.75 | TSHR (0.36) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL17546684 | 0.75 | MEN1 (0.61) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL6319788 | 0.75 | CA2 (0.38) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606095-B1 | DISULFIDE OR THIOL POLYMERIC HAIR DYES | BASF SE (DE) | 2016-10-12 | — | — | EP | disclosed |
| US-8641783-B2 | Disulfide or thiol polymeric hair dyes | BASF SE (DE) | 2014-02-04 | — | — | US | disclosed |
| US-8641783-B2 | Disulfide or thiol polymeric hair dyes | BASF SE (DE) | 2014-02-04 | — | — | US | disclosed |
| US-20130139328-A1 | DISULFIDE OR THIOL POLYMERIC HAIR DYES | BASF SE (DE) | 2013-06-06 | — | — | US | disclosed |
| US-20130139328-A1 | DISULFIDE OR THIOL POLYMERIC HAIR DYES | BASF SE (DE) | 2013-06-06 | — | — | US | disclosed |
| EP-1937780-B1 | MIXTURE OF SULFIDE DYES | BASF SE (DE) | 2013-02-13 | — | — | EP | disclosed |
| EP-1937780-B1 | MIXTURE OF SULFIDE DYES | BASF SE (DE) | 2013-02-13 | — | — | EP | disclosed |
| WO-2012022709-A1 | DISULFIDE OR THIOL POLYMERIC HAIR DYES | BASF SE (DE) | 2012-02-23 | — | — | WO | disclosed |
| EP-1893694-B1 | SULFIDE DYES | BASF SE (DE) | 2010-11-17 | — | — | EP | disclosed |
| US-7828858-B2 | Mixture of sulfide dyes | CIBA CORPORATION (US) | 2010-11-09 | — | — | US | disclosed |
| US-7828858-B2 | Mixture of sulfide dyes | CIBA CORPORATION (US) | 2010-11-09 | — | — | US | disclosed |
| US-7550016-B2 | Sulfide dyes | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-06-23 | — | — | US | disclosed |
| US-20090100610-A1 | Mixture of Sulfide Dyes | CIBA CORPORATION | 2009-04-23 | — | — | US | disclosed |
| US-20090100610-A1 | Mixture of Sulfide Dyes | CIBA CORPORATION | 2009-04-23 | — | — | US | disclosed |
| US-20090100610-A1 | Mixture of Sulfide Dyes | CIBA CORPORATION | 2009-04-23 | — | — | US | disclosed |
| US-20090049620-A1 | Sulfide dyes | CIBA SPECIALTY CHEMICAL CORP. | 2009-02-26 | — | — | US | disclosed |
| EP-1937780-A2 | MIXTURE OF SULFIDE DYES | Ciba Holding Inc. (CH) | 2008-07-02 | — | — | EP | disclosed |
| EP-1893694-A2 | SULFIDE DYES | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006136516-A2 | SULFIDE DYES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-12-28 | — | — | WO | disclosed |
| WO-2006136617-A2 | MIXTURE OF SULFIDE DYES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090100610-A1 | Mixture of Sulfide Dyes | KRT18, TST, ARSA | HDAC1 876/4885HDAC6 1063/4885HDAC3 1212/4885 |
| US-20090049620-A1 | Sulfide dyes | KRT18, C9, CBR3 | HDAC1 810/4885HDAC6 719/4885HDAC3 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.