Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582768 | 0.93 | TSHR (0.43) | CA2CA1NPC1USP2TSHR | |
| Trifluoroacetic Acid SCHEMBL7711992 | 0.86 | NPC1 (0.33) | CA2CA1NPC1USP2LMNA | |
| SCHEMBL9506089 | 0.86 | MEN1 (0.39) | CA2CA1TSHRLMNAALDH1A1 | |
| SCHEMBL9506086 | 0.82 | ALDH1A1 (0.46) | HIF1AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10036637 | 0.81 | — | — | |
| Alethine SCHEMBL689905 | 0.81 | TSHR (0.41) | CA2CA1TSHRLMNAHIF1A | |
| SCHEMBL3074874 | 0.81 | CA2 (0.44) | CA2CA1ALDH1A1MEN1KMT2A | |
| SCHEMBL9505929 | 0.78 | CA1 (0.43) | CA2CA1TSHRLMNAHIF1A | |
| SCHEMBL10490814 | 0.78 | CYP2C19 (0.43) | CA2CA1NPC1USP2TSHR | |
| SCHEMBL559906 | 0.77 | ALDH1A1 (0.56) | CA2CA1NPC1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432000-B1 | REDUCING COMPOSITION FOR PERMANENT HAIRWAVING, COMPRISING AS REDUCING AGENT AN AMINO-MERCAPTOALKYLAMIDE OR ONE OF ITS SALTS, AND ITS USE IN A PROCESS FOR PERMANENT HAIRWAVING | L'OREAL (FR) | 1993-08-11 | — | — | EP | claimed |
| US-20050222083-A1 | Thiol-modified hyaluronan | ANIKA THERAPEUTICS, INC. (US) | 2005-10-06 | — | — | US | disclosed |
| US-6884788-B2 | Thiol-modified hyaluronan | ANIKA THERAPEUTICS, INC. (US) | 2005-04-26 | — | — | US | disclosed |
| US-6852719-B2 | Dietetics; antidiabetic agents; antiinflammatory agents | PFIZER INC. (US) | 2005-02-08 | — | — | US | disclosed |
| US-20040038934-A1 | Thiol-modified hyaluronan | ANIKA THERAPEUTICS, INC. | 2004-02-26 | — | — | US | disclosed |
| US-6361777-B1 | COVALENTLY COUPLING POLYSACCHARIDE TO BIOPOLYMER HAVING HYDROXYL, AMINO AND/OR MERCAPTO GROUPS BY ACTIVATING POLYSACCHARIDE WITH CYANOGEN BROMIDE, THIOLATING WITH AMINOTHIOL LINKER, REACTING WITH BIOPOLYMER | DE STAAT DER NEDERLANDEN,VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) | 2002-03-26 | — | — | US | disclosed |
| EP-0848011-B1 | Method of coupling polysaccharides to proteins | NEDERLANDEN STAAT (NL) | 2001-03-21 | — | — | EP | disclosed |
| WO-1998027107-A1 | METHOD OF COUPLING POLYSACCHARIDES TO PROTEINS | DE STAAT DER NEDERLANDEN, VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) | 1998-06-25 | — | — | WO | disclosed |
| EP-0848011-A1 | Method of coupling polysaccharides to proteins | DE STAAT DER NEDERLANDEN VERTEGENWOORDIGD DOOR DE MINISTER VAN WELZIJN, VOLKSGEZONDHEID EN CULTUUR (NL) | 1998-06-17 | — | — | EP | disclosed |
| US-4816482-A | Radioprotective agents having an amino-thioalkyl structure | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1989-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038934-A1 | Thiol-modified hyaluronan | CD44, UACA, TST | CA2 1263/4885CA1 1632/4885NPC1 4707/4885 |
| US-20050222083-A1 | Thiol-modified hyaluronan | CD44, UACA, TST | CA2 1263/4885CA1 1632/4885NPC1 4707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.