Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | RORA | P35398 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385681 | 0.85 | RIOK2 (0.58) | RIOK2RORCUSP30ALDH1A1GAA | |
| SCHEMBL14654132 | 0.83 | SORT1 (0.47) | EPAS1ALDH1A1PDGFRBKDR | |
| SCHEMBL60505 | 0.83 | KDR (0.50) | EPAS1L3MBTL1PDGFRBKDRCSNK1D | |
| SCHEMBL3385691 | 0.83 | KCNJ5 (0.51) | ALDH1A1GAAANO1PDGFRBKDR | |
| SCHEMBL15879005 | 0.79 | SORT1 (0.50) | EPAS1ALDH1A1GAAL3MBTL1PDGFRB | |
| SCHEMBL15878263 | 0.78 | LIPE (0.48) | RIOK2EPAS1USP30ALDH1A1GAA | |
| SCHEMBL29537527 | 0.78 | CA1 (0.47) | EPAS1 | |
| SCHEMBL14630437 | 0.78 | CA1 (0.47) | EPAS1 | |
| SCHEMBL3386402 | 0.78 | EGFR (0.50) | HIF1AROCK1 | |
| SCHEMBL60104 | 0.78 | KDR (0.47) | EPAS1ALDH1A1GAAL3MBTL1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |