Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.58 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380690 | 0.85 | RIOK2 (0.46) | RIOK2RORCALDH1A1L3MBTL1ANO1 | |
| SCHEMBL14630437 | 0.84 | CA1 (0.47) | — | |
| SCHEMBL29537527 | 0.84 | CA1 (0.47) | — | |
| SCHEMBL59538 | 0.83 | KDR (0.51) | MEN1RAB9AKMT2ASMN1; SMN2PDGFRB | |
| SCHEMBL25734037 | 0.82 | LIPG (0.52) | RIOK2POLBALDH1A1L3MBTL1MAPK10 | |
| SCHEMBL3185068 | 0.81 | MAPT (0.61) | ALDH1A1MEN1KMT2ASMN1; SMN2NTRK1 | |
| SCHEMBL58603 | 0.81 | KDR (0.49) | ALDH1A1L3MBTL1MEN1RAB9AKMT2A | |
| SCHEMBL15878263 | 0.80 | LIPE (0.48) | RIOK2ALDH1A1L3MBTL1USP30GAA | |
| SCHEMBL1554002 | 0.79 | MEN1 (0.53) | RIOK2POLBALDH1A1L3MBTL1MAPK10 | |
| SCHEMBL25421609 | 0.78 | SORT1 (0.45) | RIOK2ALDH1A1L3MBTL1GAAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |