Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 11/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863591 | 0.80 | HTR7 (0.64) | HTR7HTR1APIM1PIM3CHRNB2 | |
| SCHEMBL3380848 | 0.75 | HTR6 (0.64) | HTR7HTR1AHTR6CHRNB2CHRNA4 | |
| SCHEMBL6351377 | 0.72 | HTR1A (0.64) | HTR7HTR1APIM1PIM3CHRNB2 | |
| SCHEMBL15264546 | 0.72 | HTR7 (0.48) | HTR7HTR1APIM1PIM3CHRNB2 | |
| SCHEMBL21268795 | 0.71 | HTR7 (0.71) | HTR7HTR1APIM1PIM3HTR6 | |
| SCHEMBL9690192 | 0.70 | HTR7 (0.65) | HTR7HTR1APIM1PIM3CHRNB2 | |
| SCHEMBL6743672 | 0.69 | HTR6 (0.90) | HTR6 | |
| Hydrochloric Acid SCHEMBL26136373 | 0.69 | HTR7 (0.59) | HTR7HTR1APIM1PIM3CHRNB2 | |
| SCHEMBL5526744 | 0.69 | HTR7 (1.00) | HTR7HTR1APIM1PIM3HTR6 | |
| SCHEMBL3378968 | 0.68 | HTR6 (0.62) | HTR6CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476428-B1 | PYRIDYL SULFONE DERIVATIVES AS 5-HT6 RECEPTOR LIGANDS | PHARMACIA & UPJOHN CO LLC (US) | 2010-11-17 | — | — | EP | claimed |