SCHEMBL3381024

SCHEMBL3381024

Cn1nc(C(F)(F)F)c(CS(=O)(=O)C2=NOC(C)(C)C2)c1OC1CCCC1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 3/20 0.32
PROKR1 Q8TCW9 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14364494 0.99 FPR2 (0.32) FPR2PROKR1
SCHEMBL3163535 0.90 GAA (0.32)
SCHEMBL14364496 0.87 GRM5 (0.32)
SCHEMBL14311725 0.86 GRM5 (0.33)
SCHEMBL14364512 0.86 GAA (0.32)
SCHEMBL3157387 0.86 ALDH1A1 (0.33)
SCHEMBL14364495 0.84 GAA (0.32)
SCHEMBL14802227 0.84 GAA (0.31)
SCHEMBL5393245 0.84 GAA (0.33)
Pyroxasulfone SCHEMBL3227744 0.83 GAA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404618-B2 Herbicidal composition SYNGENTA LIMITED (GB) 2013-03-26 US disclosed
US-8404618-B2 Herbicidal composition SYNGENTA LIMITED (GB) 2013-03-26 US disclosed
EP-1364946-B1 ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2010-11-24 EP disclosed
US-7833939-B2 Herbicide compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-11-16 US disclosed
EP-2186410-A1 Isoxazoline derivative and herbicide comprising the same as active ingredient KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-05-19 EP disclosed
US-20070259786-A1 Herbicidal Composition SYNGENTA CROP PROTECTION, INC. (US) 2007-11-08 US disclosed
US-20070259786-A1 Herbicidal Composition SYNGENTA CROP PROTECTION, INC. (US) 2007-11-08 US disclosed
US-7238689-B2 Isoxazoline derivative and herbicide comprising the same as active ingredient IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2007-07-03 US disclosed
US-20050256004-A1 Herbicide compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-11-17 US disclosed
US-20040110749-A1 Isoxazoline derivative and herbicide comprising the same as active ingredient KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2004-06-10 US disclosed
EP-1364946-A1 ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2003-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070259786-A1 Herbicidal Composition DDT, IDH2, ACHE FPR2 2844/4885PROKR1 3089/4885
US-20050256004-A1 Herbicide compositions DDT, CYP4X1, GLRX3 FPR2 4199/4885PROKR1 3182/4885
US-20040110749-A1 Isoxazoline derivative and herbicide comprising the same as active ingredient CYP4X1, PRDX5, CYP3A7 FPR2 3680/4885PROKR1 4027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.