SCHEMBL338116

SCHEMBL338116

Oc1ccc(SCc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.58
MAOB P27338 3/20 0.58
SLC6A4 P31645 1/20 0.53
NPC1 O15118 2/20 0.50
PPARG P37231 1/20 0.49
PPARA Q07869 1/20 0.49
HAO1 Q9UJM8 1/20 0.49
DAO P14920 1/20 0.49
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
IDO1 P14902 1/20 0.47
GRIN2A Q12879 1/20 0.45
GRIN2B Q13224 1/20 0.45
BACE1 P56817 1/20 0.45
FNTA P49354 1/20 0.45
FNTB P49356 1/20 0.45
POLB P06746 1/20 0.45
HSD17B10 Q99714 1/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5317061 0.94 HAO1 (0.56) MAOAMAOBSLC6A4NPC1PPARG
SCHEMBL7598339 0.91 MEN1 (0.53) MAOAMAOBSLC6A4NPC1PPARG
SCHEMBL3241580 0.89 MEN1 (0.50) MAOAMAOBSLC6A4NPC1MEN1
SCHEMBL332623 0.84 MAOA (0.63) MAOAMAOBSLC6A4NPC1PPARG
SCHEMBL3901203 0.83 CYP3A4 (0.52) MAOAMAOBSLC6A4NPC1PPARG
SCHEMBL155779 0.81 MAOA (0.59) MAOAMAOBMEN1KMT2AIDO1
SCHEMBL710484 0.81 TSHR (0.58) MAOAMAOBSLC6A4NPC1PPARG
SCHEMBL6076179 0.80 MAOA (0.60) MAOAMAOBSLC6A4NPC1PPARG
SCHEMBL10408225 0.79 MEN1 (0.53) NPC1DAOMEN1KMT2AIDO1
SCHEMBL8746056 0.79 MAOA (0.61) MAOAMAOBNPC1DAOMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4081597-A1 UV RESISTANT SURFACING MATERIALS FOR COMPOSITE PARTS Cytec Industries, Inc. (US) 2022-11-02 EP claimed
CN-112430404-B Check valve casting and machining process thereof 温州市海格阀门有限公司 2022-04-08 CN claimed
WO-2021133972-A1 UV RESISTANT SURFACING MATERIALS FOR COMPOSITE PARTS CYTEC INDUSTRIES INC. (US) 2021-07-01 WO claimed
CN-112430404-A Check valve casting and machining process thereof 温州市海格阀门有限公司 2021-03-02 CN claimed
EP-0505198-B1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL IND LTD (JP) 1997-01-02 EP claimed
EP-0505198-A1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-23 EP claimed
JP-63165178-A None JP disclosed
CN-117659667-B Thermosetting resin composition, anisotropic conductive film, and connection structure 常州德创高新材料科技有限公司 2024-11-01 CN disclosed
US-20240262792-A1 USP30 INHIBITORS AND USES THEREOF VINCERE BIOSCIENCES, INC. 2024-08-08 US disclosed
CN-117659667-A Thermosetting resin composition, anisotropic conductive film, and connection structure 常州德创高新材料科技有限公司 2024-03-08 CN disclosed
US-11845724-B2 USP30 inhibitors and uses thereof VINCERE BIOSCIENCES, INC. (US) 2023-12-19 US disclosed
US-11649365-B2 Ink, ink set, ink container, method of printing, and printing device RICOH COMPANY, LTD. (JP) 2023-05-16 US disclosed
EP-4081597-A1 UV RESISTANT SURFACING MATERIALS FOR COMPOSITE PARTS Cytec Industries, Inc. (US) 2022-11-02 EP disclosed
EP-0505198-A1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-23 EP disclosed
EP-0331496-B1 POLYFLUORIDE SULFONIUM COMPOUNDS AND POLYMERIZATION INITIATOR THEREOF SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1992-09-16 EP disclosed
EP-0393893-A1 Sulfonium compound and polymerisation initator comprising the sulfonium compound as the main ingredient SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1990-10-24 EP disclosed
EP-0331496-A1 Polyfluoride sulfonium compounds and polymerization initiator thereof SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1989-09-06 EP disclosed
JP-S63165178-A THERMAL RECORDING MATERIAL SEITETSU KAGAKU CO LTD 1988-07-08 JP disclosed
US-4143076-A MERCAPTO PHENOLIC AND ALKYLTHIO PHENOLIC ANTIOXIDANTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-03-06 US disclosed
US-4128530-A Mercapto phenolic and alkylthio phenolic antioxidants THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11845724-B2 USP30 inhibitors and uses thereof USP30, USP28, USP1 MAOA 4277/4885MAOB 4126/4885SLC6A4 4581/4885
US-20240262792-A1 USP30 INHIBITORS AND USES THEREOF USP30, USP28, USP1 MAOA 4277/4885MAOB 4126/4885SLC6A4 4581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.