Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381554 | 0.83 | SMN1; SMN2 (0.43) | PTGS2PTGS1LMNAADAMTS5 | |
| SCHEMBL17295145 | 0.83 | PTGS2 (0.45) | PTGS2PTGS1HTTLMNAADAMTS5 | |
| SCHEMBL17290868 | 0.83 | PTGS2 (0.45) | PTGS2PTGS1HTTLMNAADAMTS5 | |
| SCHEMBL3835167 | 0.78 | HTT (0.64) | HTTLMNA | |
| SCHEMBL19087096 | 0.77 | PTGS1 (0.42) | PTGS2PTGS1HTTLMNA | |
| SCHEMBL29248058 | 0.74 | POLB (0.50) | PTGS2PTGS1LMNA | |
| SCHEMBL15332642 | 0.73 | MAPT (0.40) | PTGS2PTGS1 | |
| SCHEMBL3379848 | 0.72 | CACNA1G (0.39) | PTGS2PTGS1LMNA | |
| SCHEMBL3384424 | 0.72 | PTGS1 (0.39) | PTGS2PTGS1LMNA | |
| SCHEMBL15331338 | 0.72 | TRPV1 (0.41) | PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1364946-B1 | ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2010-11-24 | — | — | EP | disclosed |
| US-7833939-B2 | Herbicide compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-2186410-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-05-19 | — | — | EP | disclosed |
| CN-100361982-C | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2008-01-16 | — | — | CN | disclosed |
| US-7238689-B2 | Isoxazoline derivative and herbicide comprising the same as active ingredient | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-07-03 | — | — | US | disclosed |
| CN-1257895-C | Isoxazoline derivatives and herbicides containing them as active ingredient | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2006-05-31 | — | — | CN | disclosed |
| US-20050256004-A1 | Herbicide compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| CN-1673221-A | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2005-09-28 | — | — | CN | disclosed |
| US-20040110749-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
| CN-1491217-A | Isoxazoline derivatives and herbicides containing them as active ingredient | ��Ԩ��ѧ��ҵ��ʽ���� | 2004-04-21 | — | — | CN | disclosed |
| EP-1364946-A1 | ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256004-A1 | Herbicide compositions | DDT, CYP4X1, GLRX3 | PTGS2 3715/4885PTGS1 3952/4885HTT 938/4885 |
| US-20040110749-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | CYP4X1, PRDX5, CYP3A7 | PTGS2 2491/4885PTGS1 2498/4885HTT 2681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.