SCHEMBL338222

SCHEMBL338222

Cc1nc2ccccc2n1-c1ccc(-c2c3ccccc3c(-c3ccc4ccccc4c3)c3ccccc23)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.56
HTT P42858 1/20 0.56
PIK3CD O00329 2/20 0.47
PIK3CA P42336 2/20 0.47
MTOR P42345 2/20 0.47
ALDH1A1 P00352 1/20 0.46
KDM4E B2RXH2 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP1A2 P05177 1/20 0.43
PDE10A Q9Y233 1/20 0.43
NR1H2 P55055 1/20 0.42
NR1H3 Q13133 1/20 0.42
MAPK10 P53779 1/20 0.41
POLB P06746 1/20 0.40
NPC1 O15118 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14499566 0.99 MAPK1 (0.55) MAPK1HTTPIK3CDPIK3CAMTOR
SCHEMBL2604835 0.96 MAPK1 (0.55) MAPK1HTTPIK3CDPIK3CAMTOR
SCHEMBL14499560 0.95 MAPK1 (0.51) MAPK1HTTPIK3CDPIK3CAMTOR
SCHEMBL10353566 0.93 MAPK1 (0.51) MAPK1HTTPIK3CDPIK3CAMTOR
SCHEMBL23022724 0.92 MAPK1 (0.51) MAPK1HTTPIK3CDPIK3CAMTOR
SCHEMBL14499563 0.90 MAPK1 (0.54) MAPK1HTTPIK3CDPIK3CAMTOR
SCHEMBL14499567 0.89 MAPK1 (0.50) MAPK1HTTPIK3CDPIK3CAMTOR
SCHEMBL21392575 0.89 MAPK1 (0.52) MAPK1HTTPIK3CDPIK3CAMTOR
SCHEMBL338566 0.88 ALDH1A1 (0.57) MAPK1HTTPIK3CDPIK3CAMTOR
SCHEMBL24811943 0.88 MAPK1 (0.47) MAPK1HTTPIK3CDPIK3CAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602648-B2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO (JP) 2025-03-26 EP disclosed
US-12048237-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-23 US disclosed
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-18 US disclosed
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-18 US disclosed
EP-4401530-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2024-07-17 EP disclosed
EP-3816175-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-07-17 EP disclosed
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 US disclosed
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-7851071-B2 2-[4-(10-naphthalene-2-yl-anthracene-9-yl)-phenyl]-1-phenyl-1H-benzimidazole; elevation of luminance and of efficiency in light emission even under low driving voltage IDEMITSU KOSAN CO., LTD. (JP) 2010-12-14 US disclosed
US-20100193773-A1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same IDEMITSU KOSAN CO., LTD, (JP) 2010-08-05 US disclosed
EP-2174933-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
EP-2174932-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
US-20090179554-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2009-07-16 US disclosed
US-20090179554-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2009-07-16 US disclosed
US-20070138950-A1 NITROGENOUS HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-21 US disclosed
US-20070138950-A1 NITROGENOUS HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-21 US disclosed
US-20060147747-A1 2-[4-(10-naphthalene-2-yl-anthracene-9-yl)-phenyl]-1-phenyl-1H-benzimidazole; elevation of luminance and of efficiency in light emission even under low driving voltage IDEMITSU KOSAN CO., LTD. (JP) 2006-07-06 US disclosed
EP-1602648-A1 NITROGEN-CONTAINING HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND MAPK1 4828/4885HTT 544/4885PIK3CD 3898/4885
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AOX1, SBDS, OCIAD2 MAPK1 3371/4885HTT 2883/4885PIK3CD 2346/4885
US-12041846-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 MAPK1 2329/4885HTT 3629/4885PIK3CD 3287/4885
US-20100193773-A1 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same NSD1, EED, ERG MAPK1 2216/4885HTT 2304/4885PIK3CD 2636/4885
US-12048237-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP MAPK1 4085/4885HTT 1680/4885PIK3CD 2133/4885
US-20070138950-A1 NITROGENOUS HETEROCYCLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME EHD1, HCN2, ODC1 MAPK1 1605/4885HTT 2253/4885PIK3CD 1266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.