Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13706026 | 0.72 | ALDH1A1 (0.41) | FPR1ALDH1A1LMNACNR2TSHR | |
| SCHEMBL2011805 | 0.70 | FAAH (0.38) | FPR1ALDH1A1OPRK1TSHRMAPK1 | |
| SCHEMBL6109500 | 0.68 | FAAH (0.39) | FPR1ALDH1A1LMNAATMCNR2 | |
| SCHEMBL17875026 | 0.66 | ATM (0.48) | ALDH1A1LMNAATMKDM4ETSHR | |
| SCHEMBL20994196 | 0.66 | KDM4E (0.40) | ALDH1A1LMNAATMKDM4ETSHR | |
| SCHEMBL6128412 | 0.65 | CYP3A4 (0.44) | ALDH1A1ATMKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL289929 | 0.65 | KDM4E (0.42) | ALDH1A1LMNAATMKDM4ETSHR | |
| SCHEMBL15660455 | 0.64 | FAAH (0.39) | FPR1ALDH1A1CNR2OPRK1TSHR | |
| SCHEMBL20994183 | 0.62 | ATM (0.40) | ALDH1A1LMNAATMKDM4ESMN1; SMN2 | |
| SCHEMBL289208 | 0.62 | ATM (0.40) | ALDH1A1ATMKDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625133-B1 | NITROGEN-CONTAINING MONODENTATE PHOSPHINES AND THEIR USE IN CATALYSIS | EVONIK DEGUSSA GMBH (DE) | 2016-06-29 | — | — | EP | disclosed |
| EP-2149573-A1 | Substituted indole sulfonamide compounds their preparation and use as medicaments | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2010-02-03 | — | — | EP | disclosed |
| US-7589081-B2 | Nitrogen-containing monodentate phosphines and their use in catalysis | DEGUSSA GMBH (DE) | 2009-09-15 | — | — | US | disclosed |
| US-7589081-B2 | Nitrogen-containing monodentate phosphines and their use in catalysis | DEGUSSA GMBH (DE) | 2009-09-15 | — | — | US | disclosed |
| US-7589081-B2 | Nitrogen-containing monodentate phosphines and their use in catalysis | DEGUSSA GMBH (DE) | 2009-09-15 | — | — | US | disclosed |
| US-20070123707-A1 | Nitrogen-containing monodentate phosphines and their use in catalysis | DEGUSSA AG (DE) | 2007-05-31 | — | — | US | disclosed |
| US-20070123707-A1 | Nitrogen-containing monodentate phosphines and their use in catalysis | DEGUSSA AG (DE) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123707-A1 | Nitrogen-containing monodentate phosphines and their use in catalysis | HDHD5, PNP, PHOSPHO1 | FPR1 2367/4885ALDH1A1 3129/4885LMNA 4620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.