Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAP2 | P11137 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264986 | 0.85 | MAPT (0.75) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL3382868 | 0.82 | KDM4E (0.55) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL3636076 | 0.82 | KDM4E (0.55) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL20120170 | 0.81 | EGFR (0.54) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL3384626 | 0.79 | MAP2 (0.42) | MAPTMEN1KMT2AKDM4EMAP2 | |
| SCHEMBL3382448 | 0.79 | SMN1; SMN2 (0.64) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL3382173 | 0.78 | SIRT1 (0.38) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL18029308 | 0.78 | MAPT (0.47) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL32684017 | 0.78 | MAPT (0.47) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL3231193 | 0.77 | SMN1; SMN2 (0.61) | MAPTMEN1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149551-A1 | N-(indol-3-ylalkyl)-(hetero)arylamid derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |