Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263047 | 0.85 | MAPT (0.39) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL3379855 | 0.80 | MAP2 (0.47) | SIRT1MAPTKDM4EGAAMEN1 | |
| SCHEMBL3383227 | 0.78 | MAPT (0.55) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL3230557 | 0.78 | KRAS (0.47) | MAPTMTNR1AMTNR1BARCYP1A2 | |
| SCHEMBL3261013 | 0.74 | SIRT1 (0.39) | SIRT1MAPTKDM4EGAAMEN1 | |
| SCHEMBL3639755 | 0.73 | CYP1A2 (0.41) | SIRT1MAPTKDM4EGAAMEN1 | |
| SCHEMBL3636076 | 0.72 | KDM4E (0.55) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL3261669 | 0.72 | KDM4E (0.44) | SIRT1MAPTKDM4EGAAMEN1 | |
| SCHEMBL3264690 | 0.72 | AKR1C2 (0.47) | MAPTKDM4EGAAMEN1KMT2A | |
| SCHEMBL3382968 | 0.72 | ICMT (0.38) | MAPTKDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | disclosed |