Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 18/20 | 0.39 |
| ▸ | KDR | P35968 | 16/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3186146 | 0.92 | FGFR3 (0.36) | FGFR3KDR | |
| SCHEMBL3186140 | 0.92 | FGFR3 (0.36) | FGFR3KDR | |
| SCHEMBL3381301 | 0.91 | KDR (0.35) | FGFR3KDR | |
| SCHEMBL3188986 | 0.87 | RIPK3 (0.38) | FGFR3KDR | |
| SCHEMBL3383420 | 0.86 | KDR (0.36) | FGFR3KDR | |
| SCHEMBL3178478 | 0.84 | FGFR3 (0.52) | FGFR3KDR | |
| SCHEMBL3383240 | 0.82 | FGFR3 (0.49) | FGFR3KDR | |
| SCHEMBL3380785 | 0.81 | FGFR3 (0.36) | FGFR3KDR | |
| SCHEMBL3386227 | 0.80 | KDR (0.43) | FGFR3KDR | |
| SCHEMBL3196972 | 0.80 | FGFR3 (0.35) | FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |