Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 7/20 | 0.39 |
| ▸ | KDR | P35968 | 7/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.38 |
| ▸ | WNT1 | P04628 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3202028 | 0.93 | KDR (0.41) | KDRFGFR3WNT1GSK3BDYRK1A | |
| SCHEMBL3386227 | 0.90 | KDR (0.43) | KDRFGFR3RETBDKRB1 | |
| SCHEMBL3386163 | 0.85 | WNT3A (0.42) | WNT3AKDRFGFR3 | |
| SCHEMBL3383517 | 0.83 | KDR (0.44) | KDRFGFR3 | |
| SCHEMBL3189267 | 0.82 | KDR (0.45) | WNT3AKDRFGFR3 | |
| SCHEMBL3379613 | 0.82 | KDR (0.37) | KDRFGFR3WNT1GSK3BDYRK1A | |
| SCHEMBL3386457 | 0.82 | DDR1 (0.42) | WNT3AKDRFGFR3RETBDKRB1 | |
| SCHEMBL3385477 | 0.82 | FGFR3 (0.41) | KDRFGFR3 | |
| SCHEMBL3186146 | 0.81 | FGFR3 (0.36) | KDRFGFR3 | |
| SCHEMBL3186140 | 0.81 | FGFR3 (0.36) | KDRFGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |