Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 4/20 | 0.42 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 3/20 | 0.42 |
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | BCR | P11274 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 10/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 7/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3383251 | 0.94 | DDR1 (0.47) | DDR1DDR2ABL1KITBCR | |
| SCHEMBL3202028 | 0.89 | KDR (0.41) | KDRFGFR3RETBDKRB1 | |
| SCHEMBL3385826 | 0.88 | DDR1 (0.48) | DDR1DDR2ABL1KITBCR | |
| SCHEMBL3383762 | 0.86 | KDR (0.45) | DDR1KDRFGFR3RET | |
| SCHEMBL3384104 | 0.84 | FGFR3 (0.46) | DDR1DDR2ABL1KITBCR | |
| SCHEMBL3381852 | 0.83 | KDR (0.56) | DDR1KDRFGFR3 | |
| SCHEMBL3186574 | 0.83 | KDR (0.39) | KDRFGFR3RET | |
| SCHEMBL3384343 | 0.82 | WNT3A (0.39) | KDRFGFR3RETBDKRB1WNT3A | |
| SCHEMBL3384523 | 0.82 | FGFR3 (0.46) | DDR1DDR2ABL1KITBCR | |
| SCHEMBL3386227 | 0.80 | KDR (0.43) | KDRFGFR3RETBDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |