Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | XPO1 | O14980 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389700 | 0.84 | GAA (0.52) | PDE10AHTR3APTGESHRH3 | |
| SCHEMBL3382647 | 0.82 | MCHR1 (0.43) | PDE10AHTR3AHRH3 | |
| SCHEMBL3386085 | 0.80 | PDE10A (0.42) | PDE10AHTR3AHRH3 | |
| SCHEMBL3583955 | 0.79 | HTR3E (0.54) | HTR3A | |
| SCHEMBL3384524 | 0.78 | HRH3 (0.61) | PDE10AHTR3AHRH3 | |
| SCHEMBL3384444 | 0.74 | HRH4 (0.59) | PDE10AHTR3AHRH3 | |
| SCHEMBL3570950 | 0.73 | GRIN2B (0.42) | HTR3AHRH3 | |
| SCHEMBL3574996 | 0.72 | CHRNB2 (0.56) | — | |
| SCHEMBL3537832 | 0.72 | HRH3 (0.61) | PDE10AHTR3AHRH3 | |
| SCHEMBL5832930 | 0.71 | HRH3 (0.63) | PDE10AHTR3AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984366-B1 | 3, 9-DIAZABICYCLO Ý3.3. 1¨NONANE DERIVATIVES AND THEIR USE AS MONOAMINE?NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH AS (DK) | 2010-12-15 | — | — | EP | claimed |